BIOL 1002

UWO

Course Overview

Lessons & Practice

I. Welcome

1. The Origins of Life

27min

1.1.1. The Origins of Life12 min

1.1.2. Why DNA?2 min

1.2.1. Chlamydomonas as a Model System - Theory5 min

1.2.2. Why do humans and Chlamy have a similar number of protein coding genes? - Concept Clarifier2 min

1.2.3. Mutagenesis experiments & Phototaxis - Theory5 min

1.2.4. Why are mutagenesis experiments a powerful tool? - Concept Clarifier1 min

1.3.1. Cycle 1 - Final Exam-like Practice Problems4 Qns

2. Light & Phototransduction

34min

2.1.1. Light - Theory8 min

2.1.2. Why can humans only see light in the visible spectrum? - Concept Clarifier2 min

2.2.1. What is phototransduction? - Theory7 min

2.2.2. How does Chlamydomonas undergo phototaxis? - Concept Clarifier2 min

2.2.3. Compare phototransduction in the human eye to the Chlamydomonas eye spot - Theory3 min

2.2.4. What types of mutations could be affecting these aliens who cannot see? - Concept Clarifier3 min

2.3.1. Interpreting multiple Western blots to draw conclusions - Practice Question (from Midterm 2 Test Prep)5 min

2.3.2. Mutagenesis experiment with human rod cells - Practice Question (from Midterm 2 Test Prep)3 min

2.4.1. Quiz - Cycle 1 - New!3 Qns

3. Energy & Metabolism

2.4hr

3.1.1. Overview of Metabolism4 min

3.1.2. Nutrients Required by Cells4 min

3.1.3. Practice 11 min

3.1.4. Practice 22 min

3.1.5. Practice 32 min

3.2.1. Redox (Reduction-Oxidation) Reactions7 min

3.2.2. Practice 13 min

3.2.3. Practice 23 min

3.3.1. The Laws of Thermodynamics8 min

3.3.2. Example 2 min

3.3.3. Practice2 min

3.4.1. Potential and Kinetic Energies3 min

3.4.2. Practice 11 min

3.4.3. Energy in Reactions7 min

3.4.4. Example 15 min

3.4.5. Activation Energy3 min

3.4.6. Gibbs Free Energy8 min

3.4.7. Practice 22 min

3.5.1. Coupled Reactions6 min

3.5.2. Example 1 min

3.5.3. Practice 1

3.5.4. Practice 22 min

3.6.1. ATP and the Proton Motive Force (PMF)6 min

3.6.2. Example1 min

3.6.3. Practice 2 min

3.7.1. Proteins6 min

3.7.2. Protein Folding4 min

3.7.3. Functions of Proteins7 min

3.7.4. Example1 min

3.7.5. Practice 13 min

3.7.6. Practice 2

3.7.7. Practice 3

3.7.8. Practice 4

3.8.1. Enzymes6 min

3.8.2. Enzyme Activity4 min

3.8.3. Example1 min

3.8.4. Practice 1 min

3.9.1. Enzyme Regulation10 min

3.9.2. Feedback Inhibition3 min

3.9.3. Example 13 min

3.9.4. Example 26 min

3.9.5. Practice 12 min

4. The Plasma Membrane

1.5hr

4.1.1. Lipids: Fats10 min

4.1.2. Lipids: Phospholipids5 min

4.1.3. Lipids: Steroids3 min

4.1.4. Example3 min

4.1.5. Practice 13 min

4.1.6. Practice 3

4.1.7. Practice 4

4.1.8. Practice 2

4.2.1. The Fluid Mosaic Model5 min

4.2.2. Factors Affecting Membrane Fluidity5 min

4.2.3. Practice 1

4.2.4. Practice 21 min

4.2.5. Practice 31 min

4.3.1. Thermodynamics of membrane formation9 min

4.3.2. Practice 16 min

4.4.1. Membrane Permeability3 min

4.4.2. Introduction and Passive Transport7 min

4.4.3. Practice 12 min

4.4.4. Practice 2

4.5.1. Active Transport7 min

4.5.2. Example 3 min

4.5.3. Practice 13 min

4.6.1. Osmosis and Osmolarity6 min

4.6.2. Practice 14 min

4.6.3. Practice 21 min

4.7.1. Endocytosis and Exocytosis

4.7.2. Practice 1

4.7.3. Practice 21 min

5. Cellular Respiration

1.6hr

5.1.1. Overview of Cellular Respiration4 min

5.2.1. Glycolysis4 min

5.2.2. Practice 1

5.2.3. Practice 22 min

5.2.4. Practice 3

5.3.1. Steps of Glycolysis: Intro and Stage I [Detailed]7 min

5.3.2. Steps of Glycolysis: Stages II and III [Detailed]9 min

5.3.3. Practice 1

5.3.4. Practice 2

5.3.5. Practice 3

5.3.6. Practice 4

5.4.1. Energy of Glucose Metabolism7 min

5.4.2. Practice 1

5.5.1. Glycolysis Regulation8 min

5.5.2. Practice 2

5.5.3. Practice 1

5.6.1. Glycolysis Full Sequence of Reactions and Summary [detailed]8 min

5.7.1. Pyruvate Processing4 min

5.7.2. New Practice Question

5.7.3. Stage 2: Pyruvate Processing7 min

5.7.4. Practice 1

5.8.1. The Citric Acid Cycle3 min

5.8.2. Practice 12 min

5.8.3. Practice 2

5.8.4. Practice 3

5.9.1. The Citric Acid Cycle - Substrates and Enzymes [detailed]10 min

5.9.2. Practice 1

5.9.3. Practice 3

5.9.4. Practice 2

5.10.1. Utilization of TCA Intermediates2 min

5.11.1. Electron Transport Chain Overview3 min

5.11.2. Example

5.11.3. Practice 12 min

5.11.4. Practice 23 min

5.12.1. The Electron Transport Chain8 min

5.12.2. Example

5.12.3. Practice 1

5.12.4. Practice 2

5.12.5. Practice 3

5.12.6. Practice 4

5.13.1. Fermentation3 min

5.13.2. Practice 1

5.13.3. Practice 2

5.13.4. Practice 3

6. Photosynthesis

1.1hr

6.1.1. Plant Structures for Photosynthesis4 min

6.1.2. Practice 1

6.1.3. Practice 2

6.2.1. Photosynthesis [short]9 min

6.2.2. Practice 12 min

6.2.3. Practice 2

6.3.1. Light-Dependent Reactions of Photosynthesis [detailed]10 min

6.3.2. Non-Cyclic and Cyclic Versions of Light-Dependent Reactions3 min

6.3.3. Practice 11 min

6.3.4. Practice 22 min

6.4.1. Calvin Cycle [Carbon Fixation]8 min

6.4.2. Example3 min

6.4.3. Practice 12 min

6.4.4. Practice 23 min

6.5.1. Photorespiration5 min

6.5.2. Practice 13 min

6.6.1. C4 Plants2 min

6.6.2. Practice 1

6.7.1. CAM Plants4 min

6.7.2. Practice 12 min

7. Endosymbiosis & Multicellularity

44min

8. Transcription and Translation

1.8hr

8.1.1. The Central Dogma of Biology4 min

8.1.2. Practice 1

8.1.3. Practice 22 min

8.1.4. Practice 32 min

8.2.1. Genes and mRNA8 min

8.2.2. General Structure of mRNA4 min

8.2.3. The Genetic Code8 min

8.2.4. Reading Frame3 min

8.2.5. Practice 13 min

8.2.6. Practice 22 min

8.2.7. Practice 32 min

8.2.8. Practice 43 min

8.2.9. Summary of Genes and mRNA

8.3.1. Initiation8 min

8.3.2. Elongation7 min

8.3.3. Termination4 min

8.3.4. Practice 14 min

8.3.5. Practice 22 min

8.3.6. Practice 3

8.4.1. Transcription In Eukaryotes9 min

8.4.2. Practice 1

8.5.1. RNA Maturation in Eukaryotes8 min

8.5.2. Example 3 min

8.5.3. Practice 11 min

8.5.4. Practice 23 min

8.5.5. mRNA Maturation - Theory3 min

8.6.1. Translation into Proteins9 min

8.6.2. Differences in Eukaryotic and Prokaryotic Translation3 min

8.6.3. Example 15 min

8.6.4. Example 2

8.6.5. Transcription vs. Translation Chart

8.6.6. Practice 1

8.6.7. Practice 2

9. Gene Expression & Regulation

1.2hr

9.1.1. Introduction to Regulation of Gene Expression4 min

9.1.2. Prokaryotic Levels of Regulation6 min

9.1.3. Prokaryotic Regulatory Proteins5 min

9.1.4. Types of Transcriptional Regulation5 min

9.1.5. Practice 1

9.1.6. Practice 2

9.1.7. Practice 3

9.2.1. The Tryptophan (Trp) Operon5 min

9.2.2. Trp Operon Attenuation8 min

9.2.3. The Trp Operon Summary

9.2.4. Example 1

9.2.5. Example 2

9.2.6. Practice 1

9.2.7. Practice 2

9.3.1. The Lac Operon5 min

9.3.2. Practice 1

9.3.3. Practice 2

9.3.4. Practice 3

9.4.1. The Lac Operon [detailed]5 min

9.4.2. The Lac Operon & Glucose Regulation [detailed]5 min

9.4.3. Lac Operon Summary

9.4.4. Example 1

9.4.5. Example 2

9.4.6. Practice 1

9.5.1. The Maltose (mal) Operon 4 min

9.5.2. Example 1

9.5.3. Practice 1

9.5.4. Practice 2

9.5.5. Practice 3

9.6.1. Epigenetic Gene Regulation5 min

9.6.2. X-Chromosome Inactivation4 min

9.6.3. Practice 1

9.6.4. Practice 2

9.7.1. Transcription Factors, Enhancers and Repressors3 min

9.7.2. Practice 1

9.7.3. Practice 2

9.8.1. Eukaryotic Post-Transcriptional Regulation6 min

9.8.2. Practice 1

9.8.3. Practice 2

9.9.1. Translational and Post-translational Regulation2 min

9.9.2. Practice

10. Genetics of Cancer & Other Diseases

30min

10.1.1. Causes of Cancer14 min

10.1.2. Cancer & the Cell Cycle7 min

10.1.3. Example: Oncogenes2 min

10.2.1. New Lesson4 min

10.2.2. Causes of Alzheimer’s Disease

10.3.1. MtDNA Inheritance3 min

10.3.2. Genes on mtDNA

10.3.3. Heteroplasmy

11. DNA Technologies

1.5hr

11.1.1. DNA Sequencing9 min

11.2.1. (Agarose) Gel Electrophoresis 3 min

11.3.1. Proteomics4 min

11.3.2. Chromatin Immuno-Precipitation (ChIP) 2 min

11.3.3. Practice 3

11.3.4. Practice 1

11.3.5. Practice 2

11.4.1. Southern Blot2 min

11.4.2. Example: Hybridization4 min

11.4.3. Practice

11.4.4. Northern Blot2 min

11.5.1. Homologous Recombination in Yeast8 min

11.5.2. Genome Editing11 min

11.5.3. CRISPR [detailed]9 min

11.5.4. Practice: CRISPR4 min

11.5.5. Practice 2

11.5.6. Practice 1

11.6.1. Cloning and DNA libraries17 min

11.6.2. Restriction Enzymes or Endonucleases3 min

11.6.3. Restriction Enzymes7 min

11.6.4. Gene Cloning5 min

11.6.5. Plasmids2 min

11.6.6. Digestion and ligation

12. Epigenetics

7min

12.1.1. Epigenetics2 min

12.1.2. Epigenetic Gene Regulation5 min

12.1.3. DNA Methylation

12.1.4. Practice: Epigenetics

13. The Scientific Method

5min

13.I. Chapter Intro34 sec

13.1.1. The Scientific Method5 min

13.1.2. Example

13.1.3. Example

13.1.4. Practice

13.1.5. Practice

13.Q. Scientific Method Quiz4 Qns

Mock Exams

ME.1. Midterm Exam - Mock Assessment40 Qns

ME.2. Final Exam - Mock Assessment47 Qns

ME.1 Midterm Exam - Mock Assessment

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