BIOL 239

UWaterloo

Course Overview

Lessons & Practice

I. Welcome

1. Mendelian Genetics and Probability

1.1hr

2. Modification of Mendelian Ratios

19min

2.1.1. Incomplete Dominance and Co-Dominance3 min

2.1.2. Example4 min

2.1.3. Practice 1

2.2.1. Inheritance of Autosomal Traits9 min

2.2.2. Example 1

2.2.3. Example 2

2.3.1. Inheritance of X-linked Traits

2.3.2. Example 13 min

2.3.3. Example 2

2.3.4. Example 3

3. Pedigrees

9min

3.1.1. Pedigree Analysis9 min

3.2.1. Practice 1

3.2.2. Practice 2

3.2.3. Practice 3

3.2.4. Practice 4

3.2.5. Practice 5

3.2.6. Practice 6

3.2.7. Practice 7

3.2.8. Practice 8

4. Mitosis, Meiosis, and Chromosome Numbers

1.1hr

5. Linkage, Chi Square Analysis, and Mapping

36min

5.1.1. Genetic Linkage4 min

5.1.2. The Configuration Of Linked Genes 4 min

5.1.3. The Chi-Square Test and Linkage Analysis12 min

5.1.4. Example Problem - Chi-Square Test 7 min

5.1.5. Practice 1

5.1.6. Practice 2

5.1.7. Practice 3

5.1.8. Practice 4

5.1.9. Practice Question - Chi-Square

5.1.10. Recombination Frequencies and Linkage Maps6 min

5.2.1. Gene Mapping4 min

6. DNA and the Genetic Code

1.6hr

8. DNA Cloning

34min

8.1.1. Cloning and DNA libraries17 min

8.1.2. Plasmids2 min

8.1.3. Restriction Enzymes or Endonucleases3 min

8.1.4. Restriction Enzymes7 min

8.1.5. Digestion and ligation

8.1.6. Gene Cloning5 min

9. Gene Regulation

57min

9.1.1. Introduction to Regulation of Gene Expression4 min

9.1.2. Operons 2 min

9.1.3. Types of Transcriptional Regulation5 min

9.1.4. Practice 2

9.2.1. The Lac Operon [detailed]5 min

9.2.2. The Lac Operon & Glucose Regulation [detailed]5 min

9.2.3. Lac Operon Summary

9.2.4. Example 1

9.2.5. Example 2

9.2.6. Practice 1

9.3.1. The Maltose (mal) Operon 4 min

9.3.2. Example 1

9.3.3. Practice 1

9.3.4. Practice 2

9.3.5. Practice 3

9.4.1. The Tryptophan (Trp) Operon5 min

9.4.2. Trp Operon Attenuation8 min

9.4.3. The Trp Operon Summary

9.4.4. Example 1

9.4.5. Example 2

9.4.6. Practice 1

9.4.7. Practice 2

9.5.1. Epigenetic Gene Regulation5 min

9.5.2. X-Chromosome Inactivation4 min

9.5.3. Practice 1

9.5.4. Practice 2

9.6.1. Transcription Factors, Enhancers and Repressors3 min

9.6.2. Practice 1

9.6.3. Practice 2

9.7.1. Eukaryotic Post-Transcriptional Regulation6 min

9.7.2. Practice 1

9.7.3. Practice 2

9.8.1. Translational and Post-translational Regulation2 min

9.8.2. Practice

10. Population Genetics, Mutation, and Repair

1.5hr

10.1.1. Population Genetics & Selection

10.1.2. Hardy-Weinberg Principle5 min

10.1.3. Hardy-Weinberg Equation5 min

10.1.4. Example4 min

10.1.5. Practice 1

10.1.6. Practice 2

10.1.7. Example: Applying HWE during experimentation5 min

10.1.8. Practice: Assortative Mating10 min

10.2.1. Types of DNA Mutations9 min

10.2.2. Practice 1

10.2.3. Practice 2

10.2.4. Sources of Mutation: DNA Slippage5 min

10.2.5. Sources of Mutation: Tautomeric Shifts7 min

10.2.6. Example: Tautomeric Shifts4 min

10.2.7. Sources of Mutation: Copy Number Variations3 min

10.2.8. Sources of Mutation: Mobile Elements7 min

10.3.1. Repair of Mutations During Replication [Exonuclease Activity and Mismatch Repair]10 min

10.3.2. Repair of Mutations by Mutagens [Nucleotide Excision Repair]3 min

10.3.3. Practice 12 min

10.4.1. Repair of DNA Double Stranded Breaks [detailed]9 min

10.4.2. Practice 12 min

11. Chromosomal Rearrangements, Transposable Elements, and DNA Analysis

31min

11.1.1. Duplications, Deletions and Inversions4 min

11.1.2. Practice 1

11.2.1. Transposable Elements12 min

11.2.2. Transposable Elements Example Problem3 min

11.3.1. DNA Sequencing9 min

11.4.1. (Agarose) Gel Electrophoresis 3 min

12. Cancer Genetics

36min

12.1.1. Causes of Cancer14 min

12.1.2. How does cancer grow?7 min

12.1.3. Cancer Treatments9 min

12.1.4. Example: Cancer Causes3 min

12.1.5. Example: Cancer Treatment3 min

I Welcome

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