HMB265H1

U of T

Course Overview

Grade Boosters

Lessons & Practice

1. Mendelian Genetics

1.4hr

1.1.1. History of Mendelian Genetics4 min

1.1.2. Basics of Probability for Genetics5 min

1.1.3. Example 12 min

1.1.4. Example 22 min

1.1.5. Practice 1

1.2.1. Alleles3 min

1.2.2. Genotype and Phenotype5 min

1.3.1. Mendel's Law of Segregation10 min

1.3.2. Mendel's Law of Independent Assortment6 min

1.3.3. Punnett Square Rules4 min

1.3.4. Example 15 min

1.3.5. Example 29 min

1.3.6. Practice 1

1.3.7. Practice 2

1.3.8. Practice 3

1.3.9. Practice 4

1.3.10. Cheatsheet: Inheritance Terminology

1.4.1. Forked Line Method5 min

1.4.2. Probability Method4 min

1.4.3. Practice 1

1.4.4. Practice 2

1.5.1. Pedigree Analysis9 min

1.6.1. Inheritance of Autosomal Traits9 min

1.6.2. Example 1

1.6.3. Example 2

2. Beyond Mendel's Laws

57min

2.1.1. Inheritance of X-linked Traits

2.1.2. Sex-linked Genes & Reciprocal Crosses4 min

2.1.3. Example 13 min

2.1.4. Example 2

2.1.5. Example 3

2.2.1. Incomplete Dominance and Co-Dominance3 min

2.2.2. Example4 min

2.2.3. Practice 1

2.3.1. Blood Types2 min

2.3.2. Practice 1

2.3.3. Pleiotropy, Epistasis and Polygenic Inheritance5 min

2.3.4. Practice 2

2.3.5. Example: Epistasis5 min

2.3.6. Practice 3

2.4.1. Practice 1

2.4.2. Practice 2

2.4.3. Practice 3

2.4.4. Practice 4

2.4.5. Practice 5

2.4.6. Practice 6

2.4.7. Practice 7

2.4.8. Practice 8

2.5.1. Practice 1

2.5.2. Practice 2

2.5.3. Practice 3

2.6.1. Complementation 7 min

2.6.2. Example Problem2 min

2.6.3. Practice Question 4 min

2.6.4. Epistasis 5 min

2.6.5. Redundancy 2 min

2.6.6. Practice Question 2 min

2.6.7. Genes in a pathway 3 min

2.6.8. Penetrance versus Expressivity 1 min

2.6.9. Example Problem4 min

2.6.10. Cheatsheet - Summary of genetic interactions

3. Review - DNA Replication

39min

3.1.1. Review of DNA Structure10 min

3.1.2. Practice 12 min

3.1.3. Practice 2

3.2.1. DNA Replication in Cells14 min

3.2.2. Example: Leading and Lagging Strands2 min

3.2.3. Practice 12 min

3.2.4. Practice 23 min

3.2.5. Example: Complete the Replication Bubble4 min

4. Gene Expression

1.4hr

4.1.1. The Central Dogma of Biology4 min

4.1.2. Practice 1

4.1.3. Practice 22 min

4.1.4. Practice 32 min

4.2.1. Genes and mRNA8 min

4.2.2. General Structure of mRNA4 min

4.2.3. The Genetic Code8 min

4.2.4. Reading Frame3 min

4.2.5. Practice 13 min

4.2.6. Practice 22 min

4.2.7. Practice 32 min

4.2.8. Practice 43 min

4.2.9. Summary of Genes and mRNA

4.3.1. Transcription In Eukaryotes9 min

4.3.2. Practice 1

4.4.1. RNA Maturation in Eukaryotes8 min

4.4.2. Example 3 min

4.4.3. Practice 11 min

4.4.4. Practice 23 min

4.4.5. mRNA Maturation - Theory3 min

4.5.1. Translation into Proteins9 min

4.5.2. Differences in Eukaryotic and Prokaryotic Translation3 min

4.5.3. Example 15 min

4.5.4. Example 2

4.5.5. Transcription vs. Translation Chart

4.5.6. Practice 1

4.5.7. Practice 2

7. Population Genetics

59min

7.1.1. Evolution of Populations5 min

7.1.2. Example2 min

7.1.3. Practice46 sec

7.1.4. Practice46 sec

7.1.5. Practice1 min

7.1.6. Graphing Allele Frequencies Over Time7 min

7.1.7. Practice: Relative Fitness5 min

7.2.1. Hardy-Weinberg Principle5 min

7.2.2. Hardy-Weinberg Equation5 min

7.2.3. Example4 min

7.2.4. Example: Applying HWE during experimentation5 min

7.2.5. Practice

7.2.6. Practice

7.2.7. Practice: Assortative Mating10 min

7.2.8. Practice Question 1.

7.2.9. Practice Question 2.2 min

7.2.10. Practice Question 3. 5 min

8. Lab Techniques for Genetics

47min

8.1.1. Polymerase Chain Reaction (PCR)10 min

8.1.2. Primer Design3 min

8.1.3. Example 15 min

8.1.4. Practice 12 min

8.1.5. Practice 2

8.2.1. Gene Cloning5 min

8.2.2. Plasmids2 min

8.2.3. Restriction Enzymes or Endonucleases3 min

8.3.1. DNA Sequencing9 min

8.4.1. (Agarose) Gel Electrophoresis 3 min

8.5.1. Southern Blot2 min

8.5.2. Northern Blot2 min

8.5.3. Practice

9. Genetic Variation

16min

9.1.1. Additive Inheritance 8 min

9.1.2. Environmental Modification 6 min

9.1.3. Example Problem 2 min

9.1.4. Practice Question1 min

9.Q. Checkpoint Quiz9 Qns

10. Mutations

1.4hr

10.1.1. Types of DNA Mutations9 min

10.1.2. Practice 1

10.1.3. Practice 2

10.1.4. Sources of Mutation: Tautomeric Shifts7 min

10.1.5. Example: Tautomeric Shifts4 min

10.1.6. Sources of Mutation: DNA Slippage5 min

10.1.7. Sources of Mutation: Copy Number Variations3 min

10.1.8. Sources of Mutation: Mobile Elements7 min

10.1.9. Transposable Elements 6 min

10.2.1. Repair of Mutations During Replication [Exonuclease Activity and Mismatch Repair]10 min

10.2.2. Repair of Mutations by Mutagens [Nucleotide Excision Repair]3 min

10.2.3. Practice 12 min

10.3.1. Repair of DNA Double Stranded Breaks [detailed]9 min

10.3.2. Practice 12 min

10.4.1. Duplications, Deletions and Inversions4 min

10.4.2. Practice 1

10.5.1. Chromosomal Nondisjunction, Aneuploidy and Polyploidy6 min

10.5.2. Changes in Chromosomal Numbers

10.5.3. Example2 min

10.5.4. Practice 1

10.5.5. Practice 27 min

11. Epigenetics

9min

11.1.1. Epigenetic Gene Regulation5 min

11.1.2. X-Chromosome Inactivation4 min

11.1.3. Practice 1

11.1.4. Practice 2

12. Genetics & Development

17min

12.1.1. Model organisms2 min

12.2.1. Drosophila Development9 min

12.2.2. What would a bicoid knockout mutant fly look like? A bicoid overexpression mutant?1 min

12.2.3. Segmentation genes and development5 min

13. Gene Editing

19min

13.1.1. Genome Editing11 min

13.1.2. CRISPR [detailed]9 min

13.1.3. Practice 1

13.1.4. Practice 2

14. Cancer Genetics

33min

14.1.1. Causes of Cancer14 min

14.1.2. Cancer - Theory7 min

14.1.3. Cancer Treatments9 min

14.1.4. Example: Cancer Causes3 min

14.1.5. New Practice Question

14.1.6. New Practice Question

14.1.7. Cancer biology

14.1.8. New Practice Question

Mock Exams

ME.1. Mock Exam10 Qns

ME.2. Mock Exam10 Qns

ME.3. Mock Exam5 Qns

HMB265H1 Grade Boosters

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Final Mock Exam

A realistic practice exam with solution breakdowns.

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