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Gibbs Free Energy

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Wize University Biology Textbook > Energy & Metabolism

Types of Energy [Potential, Kinetic, Free & Activation]

7 Activities

Wize University Biology Textbook > Energy & Metabolism

Coupled Reactions

4 Activities

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Mark Yourself Question
  1. Grab a piece of paper and try this problem yourself.
  2. When you're done, check the "I have answered this question" box below.
  3. View the solution and report whether you got it right or wrong.
Which of the following is true about an exergonically coupled reaction? Select all that apply.

  1. The net ΔG is negative
  2. There are more than 2 reactions happening at the same time
  3. One reaction has a positive ΔG while another has a negative ΔG
  4. many of these reactions are used to increase molecular complexity
More Types of Energy [Potential, Kinetic, Free & Activation] Questions:
C6H12O6 + 6O2 --> 6CO2 +6H2O is the balanced chemical equation for respiration. Is the process exergonic or endergonic?
Why is the gibbs free energy change for ATP +H2O -> ADP +Pi a greater negative value than the gibbs free energy change for AMP +H2O -> Adenosine + Pi?
Coupled Reactions
What is the gibbs free energy of reaction for a coupled reaction where one process has a standard free energy change of +43 kJ/mol and the other has a standard free energy change of -16kJ/mol?
Is this coupled reaction spontaneous or non-spontaneous?
High transfer potential: Similar to 2014 Question 8
Which of the following reactions has the most negative free energy change?
Free Energy
How can unfavourable reactions occur in a cell?
Which of the following have a negative ΔG?
Wize Exam Practice Questions:
Which of the following enzymes catalyzes a reversible reaction?
Similar to 2018 exam Q4
Provide 2 examples of coupled reactions found in cellular respiration, then give a detailed explanation of each. Use free energy values were necessary (6pts)
Free Energy Diagram
Which letter represents the energy of activation of the reaction in the absence of enzyme? Which letter represents the free energy of the reaction?
If the entropy of a system is large, the enthalpy is negative and the temperature of the system is high, which of the following would be correct? All other conditions are constant and controlled. Select all that apply.
High transfer potential: Similar to 2014 Question 8
Which of the following reactions has the most negative free energy change?
Coupled Reactions
What is the gibbs free energy of reaction for a coupled reaction where one process has a standard free energy change of +43 kJ/mol and the other has a standard free energy change of -16kJ/mol?
Is this coupled reaction spontaneous or non-spontaneous?
Why is the gibbs free energy change for ATP +H2O -> ADP +Pi a greater negative value than the gibbs free energy change for AMP +H2O -> Adenosine + Pi?
What is the net free energy change of two reactions and indicate if it is favourable or unfavourabe. One with a free energy change of -26 kJ/mol and the other with +15 kJ/mol.
Practice: Enzyme Catalyzed Reactions
What is FALSE about this energy diagram of an uncatalyzed reaction?
Practice: Polymerization
Polymerization reactions are endergonic, why?
Free Energy
How can unfavourable reactions occur in a cell?
A bike at the top of a mountain represents what type of energy? [1 word]
Practice: What is Gibbs Free Energy?
What does Gibbs free energy determine?
Which of the following statements about protein folding is correct?
i. The native conformation of a protein is determined by the structure with the lowest free energy
ii. Denaturation of a protein results from high temperatures or exposure to chemicals like urea
Practice: Thermodynamics
Which enthalpic and entropic combinations will result in a spontaneous bilayer formation?
Which of the following would result in spontaneous membrane transport?
Using Gibb's Free Energy, an example
A biochemical pathway produces metabolite E. This pathway consists of A, B, C and D intermediates that require enzymes 1, 2, 3 and 4 to catalyze each step of the reaction.
a. Given the following information about each reaction, state which reactions are exergonic or endergonic. Where possible, state which reactions are exothermic or endothermic.
i. A → B, ΔG = +3
Given the Gibb's Free Energy of a reaction, predict if the reaction is spontaneous
Given the below steps to a biological reaction, what can you infer about each step? What can you predict about the reaction as a whole?
Using Gibb's Free Energy, an example
A biochemical pathway produces metabolite E. This pathway consists of A, B, C and D intermediates that require enzymes 1, 2, 3 and 4 to catalyze each step of the reaction.
a. Given the following information about each reaction, state which reactions are exergonic or endergonic. Where possible, state which reactions are exothermic or endothermic.
i. A → B, ΔG = +3
Given the below steps to a biological reaction, what can you infer about each step? What can you predict about the reaction as a whole?
(i.e. what is ΔGTotal\Delta G_{Total} )
C6H12O6 + 6O2 --> 6CO2 +6H2O is the balanced chemical equation for respiration. Is the process exergonic or endergonic?
When a misfolded protein is being linearlized by the proteasome it requires ATP, why?
Given the figure, which of the following statements is correct?
Which of the following are accurate statements regarding membrane transport?
i. The entropy of the system decreases during active transport which is why it requires the use of ATP
ii. Passive diffusion functions because of an increase in entropy
Why are enzymes vital for life?
Given the following information, what is the value of the change in free energy?
T = 25oC
Entropy of the reactants = 3
Given the figure below, which of the following is true?
Which of the following statements best describes the enthalpy change of a reaction?
Which of the following enzymes catalyzes a reversible reaction?
A reaction with a positive ΔG is considered...
Which of the following have a negative ΔG?
Which of the following is true regarding non-spontaneous reactions?
Why are ADP + inorganic phosphate (Pi) more stable than ATP?
Fill in the blanks: Spontaneous reactions are _____________, and have a _____________ change in free energy.
How does energy coupling work?
Which of the following is true regarding non-spontaneous reactions?
Which of the following enzymes catalyzes an unfavorable reaction?
More Coupled Reactions Questions:
C6H12O6 + 6O2 --> 6CO2 +6H2O is the balanced chemical equation for respiration. Is the process exergonic or endergonic?
Coupled Reactions
What is the gibbs free energy of reaction for a coupled reaction where one process has a standard free energy change of +43 kJ/mol and the other has a standard free energy change of -16kJ/mol?
Is this coupled reaction spontaneous or non-spontaneous?
Free Energy
How can unfavourable reactions occur in a cell?
Which of the following have a negative ΔG?
Wize Exam Practice Questions:
Which of the following enzymes catalyzes a reversible reaction?
What are the 3 steps of glycolysis that have the largest exergonic reactions? What enzymes are they regulated by?
Similar to 2018 exam Q4
Provide 2 examples of coupled reactions found in cellular respiration, then give a detailed explanation of each. Use free energy values were necessary (6pts)
Give a real-life example of an ATP coupled reaction. Write out the equations.
If the entropy of a system is large, the enthalpy is negative and the temperature of the system is high, which of the following would be correct? All other conditions are constant and controlled. Select all that apply.
Coupled Reactions
What is the gibbs free energy of reaction for a coupled reaction where one process has a standard free energy change of +43 kJ/mol and the other has a standard free energy change of -16kJ/mol?
Is this coupled reaction spontaneous or non-spontaneous?
What is the net free energy change of two reactions and indicate if it is favourable or unfavourabe. One with a free energy change of -26 kJ/mol and the other with +15 kJ/mol.
Practice: Polymerization
Polymerization reactions are endergonic, why?
Free Energy
How can unfavourable reactions occur in a cell?
Practice: What is Gibbs Free Energy?
What does Gibbs free energy determine?
Using Gibb's Free Energy, an example
A biochemical pathway produces metabolite E. This pathway consists of A, B, C and D intermediates that require enzymes 1, 2, 3 and 4 to catalyze each step of the reaction.
a. Given the following information about each reaction, state which reactions are exergonic or endergonic. Where possible, state which reactions are exothermic or endothermic.
i. A → B, ΔG = +3
Given the below steps to a biological reaction, what can you infer about each step? What can you predict about the reaction as a whole?
(i.e. what is ΔGTotal\Delta G_{Total} )
C6H12O6 + 6O2 --> 6CO2 +6H2O is the balanced chemical equation for respiration. Is the process exergonic or endergonic?
Given the figure, which of the following statements is correct?
Why are enzymes vital for life?
Given the following information, what is the value of the change in free energy?
T = 25oC
Entropy of the reactants = 3
Given the figure below, which of the following is true?
Which of the following statements best describes the enthalpy change of a reaction?
Which of the following enzymes catalyzes a reversible reaction?
A reaction where the products have less energy than the reactants is considered…
A reaction with a positive ΔG is considered...
Why is ATP hydrolysis exergonic?
How can energy coupling with ATP be described?
Which of the following is not a reason ATP hydrolysis is exergonic?
Which of the following describes a reaction that occurs on its own and releases energy?
Which of the following have a negative ΔG?
How does energy coupling work?