BIOL 2004

VT

Course Overview

Lessons & Practice

I. Welcome

1. The Scientific Method

5min

1.I. Chapter Intro34 sec

1.1.1. The Scientific Method5 min

1.1.4. Practice

1.1.5. Practice

1.Q. Scientific Method Quiz4 Qns

2. Introduction to Genetics

12min

2.1.1. History of Mendelian Genetics4 min

2.2.1. Alleles3 min

2.2.2. Genotype and Phenotype5 min

3. DNA Structure

19min

3.1.1. Nucleic Acid Structure Theory7 min

3.1.2. Review of DNA Structure10 min

3.1.3. Practice 12 min

3.1.4. Practice 2

4. DNA Replication

57min

4.1.1. DNA Replication - The Steps4 min

4.1.2. DNA Replication in Cells14 min

4.1.3. DNA polymerase Theory5 min

4.1.4. Example: Leading and Lagging Strands2 min

4.1.5. Practice 12 min

4.1.6. Practice 23 min

4.1.7. New Lesson53 sec

4.1.8. Example: Complete the Replication Bubble4 min

4.2.1. Meselson-Stahl Experiment9 min

4.2.2. Example: Applying the Meselson-Stahl Experiment2 min

4.2.3. Practice 12 min

4.3.1. Telomerase4 min

4.3.2. Practice 11 min

4.3.3. Practice 22 min

5. Transcription & RNA

1.6hr

6. Translation

16min

6.1.1. Translation into Proteins9 min

6.1.2. Differences in Eukaryotic and Prokaryotic Translation3 min

6.1.3. Example 15 min

6.1.4. Example 2

6.1.5. Transcription vs. Translation Chart

6.1.6. Practice 1

6.1.7. Practice 2

7. Gene Mutation & Repair

1.3hr

7.1.1. Types of DNA Mutations9 min

7.1.2. Practice 1

7.1.3. Practice 2

7.1.4. Sources of Mutation: DNA Slippage5 min

7.1.5. Sources of Mutation: Tautomeric Shifts7 min

7.1.6. Example: Tautomeric Shifts4 min

7.1.7. Sources of Mutation: Copy Number Variations3 min

7.1.8. Sources of Mutation: Mobile Elements7 min

7.2.1. Repair of Mutations During Replication [Exonuclease Activity and Mismatch Repair]10 min

7.2.2. Repair of Mutations by Mutagens [Nucleotide Excision Repair]3 min

7.2.3. Practice 12 min

7.3.1. Repair of DNA Double Stranded Breaks [detailed]9 min

7.3.2. Practice 12 min

7.4.1. Chromosomal Nondisjunction, Aneuploidy and Polyploidy6 min

7.4.2. Example2 min

7.4.3. Practice 1

7.4.4. Practice 27 min

8. Chromosome Structure & Organelle DNA

26min

8.1.1. The Gene and the Genome10 min

8.1.2. Practice 11 min

8.2.1. Endosymbiont Theory7 min

8.2.2. endosymbiosis

8.2.3. Endosymbiosis

8.2.4. Endosymbiosis Practice1 min

8.2.5. Wize Concept Check

8.3.1. Lateral Gene Transfer5 min

10. Chromosomal Variation

19min

10.1.1. Duplications, Deletions and Inversions4 min

10.1.2. Practice 1

10.2.1. Chromosomal Nondisjunction, Aneuploidy and Polyploidy6 min

10.2.2. Example2 min

10.2.3. Practice 1

10.2.4. Practice 27 min

11. Control of Gene Expression

1hr

11.1.1. Introduction to Regulation of Gene Expression4 min

11.1.2. Prokaryotic Levels of Regulation6 min

11.1.3. Prokaryotic Regulatory Proteins5 min

11.1.4. Types of Transcriptional Regulation5 min

11.1.5. Practice 1

11.1.6. Practice 2

11.1.7. Practice 3

11.2.1. The Tryptophan (Trp) Operon5 min

11.2.2. Trp Operon Attenuation8 min

11.2.3. The Trp Operon Summary

11.2.4. Example 1

11.2.5. Example 2

11.2.6. Practice 1

11.2.7. Practice 2

11.3.1. The Lac Operon5 min

11.3.2. Practice 1

11.3.3. Practice 2

11.3.4. Practice 3

11.4.1. The Lac Operon [detailed]5 min

11.4.2. The Lac Operon & Glucose Regulation [detailed]5 min

11.4.3. Lac Operon Summary

11.4.4. Example 1

11.4.5. Example 2

11.4.6. Practice 1

11.5.1. The Maltose (mal) Operon 4 min

11.5.2. Example 1

11.5.3. Practice 1

11.5.4. Practice 2

11.5.5. Practice 3

11.6.1. Transcription Factors, Enhancers and Repressors3 min

11.6.2. Practice 1

11.6.3. Practice 2

11.7.1. Eukaryotic Post-Transcriptional Regulation6 min

11.7.2. Practice 1

11.7.3. Practice 2

11.8.1. Translational and Post-translational Regulation2 min

11.8.2. Practice

12. Basic Principles of Heredity

48min

12.1.1. History of Mendelian Genetics4 min

12.1.2. Basics of Probability for Genetics5 min

12.1.3. Example 12 min

12.1.4. Example 22 min

12.1.5. Practice 1

12.2.1. Mendel's Law of Segregation10 min

12.2.2. Mendel's Law of Independent Assortment6 min

12.2.3. Punnett Square Rules4 min

12.2.4. Example 15 min

12.2.5. Example 29 min

12.2.6. Practice 1

12.2.7. Practice 2

12.2.8. Practice 3

12.2.9. Practice 4

12.2.10. Cheatsheet: Inheritance Terminology

13. Sex Determination & Linkage

6min

13.1.1. Sex Determination3 min

13.2.1. Inheritance of X-linked Traits

13.2.2. Example 13 min

13.2.3. Example 2

13.2.4. Example 3

14. Extensions to Basic Principles

19min

14.1.1. Incomplete Dominance and Co-Dominance3 min

14.1.2. Example4 min

14.1.3. Practice 1

14.2.1. Practice 1

14.2.2. Practice 2

14.2.3. Practice 3

14.3.1. Blood Types2 min

14.3.2. Practice 1

14.3.3. Pleiotropy, Epistasis and Polygenic Inheritance5 min

14.3.4. Practice 2

14.3.5. Example: Epistasis5 min

14.3.6. Practice 3

15. Pedigrees

18min

15.1.1. Pedigree Analysis9 min

15.2.1. Inheritance of Autosomal Traits9 min

15.2.2. Example 1

15.2.3. Example 2

15.3.1. Practice 1

15.3.2. Practice 2

15.3.3. Practice 3

15.3.4. Practice 4

15.3.5. Practice 5

15.3.6. Practice 6

15.3.7. Practice 7

15.3.8. Practice 8

16. Linkage Analysis

16min

16.1.1. Genetic Linkage4 min

16.1.2. Recombination Frequencies and Linkage Maps6 min

16.1.3. Practice 1

16.1.4. Practice 2

16.1.5. Practice 3

16.1.6. Practice 4

16.2.1. Gene mapping6 min

16.2.2. Genetic mapping

16.2.3. New Practice Question

16.2.4. New Practice Question

17. Bacterial & Viral Genetics

18min

17.1.1. Prokaryotes6 min

17.1.2. Practice

17.1.3. Practice

17.1.4. Practice

17.2.1. Prokaryotic Growth Phases3 min

17.2.2. Practice 1

17.2.3. Practice 2

17.3.1. Binary Fission: Prokaryotic Cytokinesis3 min

17.3.2. Practice 1

17.4.1. Viral Morphology and Diversity3 min

17.4.2. Practice

17.4.3. Practice

17.5.1. Viral Infections3 min

17.5.2. Practice

17.5.3. Practice

18. Molecular Biology Techniques

1.2hr

18.1.1. (Agarose) Gel Electrophoresis 3 min

18.2.1. Southern Blot2 min

18.2.2. Northern Blot2 min

18.2.3. Practice

18.3.1. Genome Editing11 min

18.3.2. CRISPR [detailed]9 min

18.3.3. Practice 1

18.3.4. Practice 2

18.4.1. Gene Cloning5 min

18.4.2. Plasmids2 min

18.4.3. Restriction Enzymes or Endonucleases3 min

18.5.1. Polymerase Chain Reaction (PCR)10 min

18.5.2. Primer Design3 min

18.5.3. Example 15 min

18.5.4. Practice 12 min

18.5.5. Practice 2

18.6.1. Cloning and DNA Libraries17 min

19. Genomics & Proteomics

42min

19.1.1. Gene Mapping4 min

19.2.1. Karyotyping3 min

19.2.2. Practice

19.3.1. DNA Sequencing9 min

19.4.1. Centrifugation2 min

19.4.2. Chromatography4 min

19.4.3. Practice

19.5.1. Protein Detection Techniques6 min

19.5.2. SDS-PAGE (Electrophoresis)6 min

19.5.3. Mass Spectrometry2 min

19.5.4. Practice 1

19.6.1. Proteomics4 min

19.6.2. Chromatin Immuno-Precipitation (ChIP) 2 min

19.6.3. Practice 1

19.6.4. Practice 2

19.6.5. Practice 3

20. Epigenetics

9min

20.1.1. Epigenetic Gene Regulation5 min

20.1.2. X-Chromosome Inactivation4 min

20.1.3. Practice 1

20.1.4. Practice 2

21. Population Genetics

33min

21.1.1. Population Genetics & Selection

21.1.2. Hardy-Weinberg Principle5 min

21.1.3. Hardy-Weinberg Equation5 min

21.1.4. Example4 min

21.1.5. Practice 1

21.1.6. Practice 2

21.1.7. population Genetics & Selection

21.1.8. New Lesson3 min

21.1.9. Example: Applying HWE during experimentation5 min

21.1.10. Practice: Assortative Mating10 min

22. Evolutionary Genetics

22min

22.I. Intro: Evolution31 sec

22.1.1. Descent with Modification6 min

22.1.2. Practice

22.1.3. Practice

22.1.4. Practice

22.1.5. Practice

22.2.1. Origin of Species9 min

22.2.2. Practice

22.2.3. Practice

22.2.4. Practice

22.3.1. The Modern Synthesis6 min

22.3.2. Practice

22.3.3. Practice

22.Q. Quiz: Evolution8 Qns

Mock Exams

ME.1. Exam 3 - Mock Assessment27 Qns

ME.2. Exam 4 - Mock Assessment38 Qns

ME.3. Final Exam - Mock Assessment117 Qns

ME.2 Exam 4 - Mock Assessment

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