BIOCH 200

U of A

Course Overview

Lessons & Practice

1. Biomolecules

1hr

1.1.1. From Monomers to Polymers4 min

1.2.1. Functional Groups12 min

1.2.2. Example: Functional Groups 2 min

1.2.3. Functional Groups and Naming5 min

1.3.1. Unique Properties of Water6 min

1.3.2. Practice 22 min

1.4.1. Types of Chemical Bonds 5 min

1.4.2. Practice 1

1.4.3. Practice 2

1.5.1. Intermolecular Forces: Hydrogen Bonding5 min

1.5.2. Example 2 min

1.5.3. Practice 12 min

1.5.4. Practice 22 min

1.5.5. Practice 33 min

1.6.1. Intermolecular Forces: Van der Waals Interactions 11 min

1.6.2. Practice 13 min

1.6.3. Practice 2

1.Q. Checkpoint Quiz5 Qns

2. Protein Structure and Function: What Do Proteins Do?

48min

2.1.1. Amino Acids10 min

2.1.2. Example: Similar Amino Acids3 min

2.1.3. Example: Directed Mutagenesis3 min

2.2.1. Acids-Base Definitions, pH, pKa5 min

2.2.2. pKa and Ionization State8 min

2.2.3. pKa of Amino Acids10 min

2.2.4. Amino Acid Isoelectric Point5 min

2.2.5. Practice: pKa of Side Chains4 min

2.Q. Checkpoint Quiz8 Qns

3. Protein Structure and Function: Primary, Secondary, Tertiary and Quaternary

1.5hr

3.1.1. Hydrogen Bonds4 min

3.1.2. Hydrophobic Interactions4 min

3.1.3. Electrostatic/Ionic Interactions3 min

3.1.4. Van der Waals Forces3 min

3.1.5. Disulfide Bond3 min

3.1.6. Example: Hydrogen Bonding3 min

3.1.7. Example: Non-Covalent Bonds4 min

3.1.8. Practice: Amino Acid Hydrophobicity5 min

3.2.1. Peptide Bond6 min

3.2.2. Peptide Bond Angles3 min

3.2.3. Example: Peptide Chain4 min

3.2.4. Example: Peptide Bond Angles2 min

3.2.5. Practice: Peptide Bond Resonance2 min

3.3.1. Primary and Secondary Protein Structure5 min

3.3.2. Example: Point Mutation in Secondary Structure3 min

3.4.1. α-helix3 min

3.4.2. Properties of α-helix5 min

3.4.3. Example: Properties of an Alpha Helix3 min

3.4.4. Example: Point Mutation in Alpha Helix4 min

3.4.5. Practice: Alpha-Helix3 min

3.5.1. β-Sheet4 min

3.5.2. Example: H-bonding in Beta-Sheets2 min

3.6.1. Tertiary and Quarternary Protein Structure9 min

3.6.2. Example: Tertiary Structure (Motifs)3 min

3.6.3. Practice: Quaternary Structure3 min

3.Q. Checkpoint Quiz7 Qns

4. The Structure and Function of Myoglobin and Hemoglobin

23min

4.1.1. Myoglobin1 min

4.1.2. Hemoglobin10 min

4.1.3. Dissorders in Hemoglobin2 min

4.1.4. Ligand Binding10 min

4.1.5. Hemoglobin Regulation

4.1.6. New Practice Question

4.1.7. Myoglobin

4.Q. Checkpoint Quiz3 Qns

5. Enzymes

56min

6. Biological Membranes

1.4hr

6.1.1. Introduction to Lipids2 min

6.1.2. Fatty Acids7 min

6.1.3. Triacylglycerols2 min

6.1.4. Glycerophospholipids3 min

6.1.5. Sphingolipids2 min

6.1.6. Cholesterol3 min

6.1.7. Steroids3 min

6.1.8. Example: Naming Fatty Acids3 min

6.1.9. Example: Identifying Lipids1 min

6.1.10. Practice: Fatty Acids1 min

6.2.1. The Lipid Bilayer6 min

6.2.2. Membrane Lipid Assembly3 min

6.2.3. Membrane Fluidity8 min

6.2.4. Membrane Lipid Dynamics2 min

6.2.5. Example: Membrane Fluidity1 min

6.2.6. Example: Cellular Membranes2 min

6.2.7. Practice: Transverse Diffusion of Lipids1 min

6.3.1. Proteins in the Lipid Bilayer1 min

6.3.2. Peripheral Membrane Proteins5 min

6.3.3. Integral Membrane Proteins5 min

6.3.4. Practice: Peripheral Membrane Proteins1 min

6.3.5. Practice: Integral Membrane Proteins1 min

6.4.1. Introduction and Passive Transport7 min

6.4.2. Active Transport7 min

6.4.3. Example: Active vs. Passive Transport5 min

6.4.4. Practice: Membrane Proteins

6.Q. Lipids and Biological Membranes7 Qns

7. Introduction to Metabolism

41min

7.1.1. Intro to Metabolism7 min

7.1.2. Gibbs Free Energy10 min

7.1.3. High Energy Intermediates9 min

7.1.4. Oxidation-Reduction Reactions6 min

7.1.5. Example: Oxidation-Reduction Reactions3 min

7.1.6. Example: Gibbs Free Energy3 min

7.1.7. Free energy of ATP52 sec

7.1.8. Coupled Reactions1 min

7.Q. Introduction to Metabolism4 Qns

8. Oxidative phosphorylation

37min

8.1.1. Electron Transporters6 min

8.1.2. The Electron Transport Chain8 min

8.1.3. ATP and the Proton Motive Force (PMF)6 min

8.1.4. ATP Synthesis10 min

8.1.5. Electron Transport Inhibitors3 min

8.1.6. Electron Transporters49 sec

8.1.7. The electron transport chain1 min

8.1.8. Electron Transport Inhibitors42 sec

8.1.9. ATP production: Cheatsheet

8.Q. Checkpoint Quiz7 Qns

9. Glucose Metabolism

52min

9.1.1. Glycolysis11 min

9.1.2. Glycolysis Regulation4 min

9.1.3. ATP production in Glycolysis1 min

9.1.4. Triose Phosphate Isomerase2 min

9.1.5. Glycolysis Regulation41 sec

9.1.6. Glycolysis: Cheatsheet

9.2.1. Pyruvate Dehydrogenase6 min

9.2.2. Example: Pyruvate dehydrogenase4 min

9.3.1. Lactate Fermentation2 min

9.3.2. Alcohol Fermentation42 sec

9.3.3. Anaerobic Metabolism1 min

9.3.4. Lactate Formation55 sec

9.3.5. Anaerobic respiration30 sec

9.4.1. Glycogen Synthesis and Breakdown10 min

9.4.2. Example: Carbohydrate Metabolism- BIOCH22803 min

9.4.3. Example: Polysaccharide Structure-BIOCH22803 min

9.Q. Checkpoint Quiz6 Qns

10. The Citric Acid Cycle

13min

10.1.1. Structure of Mitochondria3 min

10.1.2. Citric Acid Cycle8 min

10.1.3. The Citric Acid Cycle1 min

10.1.4. The Citric Acid Cycle: Cheatsheet

10.Q. Checkpoint Quiz5 Qns

Mock Exams

ME.1. Midterm - Mock Assessment46 Qns

ME.2. Midterm - Mock Assessment65 Qns

ME.3. Final Exam - Mock Assessment72 Qns

ME.2 Midterm - Mock Assessment

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