BIOL 201

UBC

Course Overview

Lessons & Practice

I. Welcome

1. Intermolecular interactions

28min

1.1.1. Hydrogen Bonds4 min

1.1.2. Hydrophobic Interactions4 min

1.1.3. Electrostatic/Ionic Interactions3 min

1.1.4. Van der Waals Forces3 min

1.1.5. Disulfide Bond3 min

1.1.6. Example: Hydrogen Bonding3 min

1.1.7. Example: Non-Covalent Bonds4 min

1.1.8. Practice: Amino Acid Hydrophobicity5 min

2. Proteins

2.2hr

2.1.1. Primary and Secondary Protein Structure2 min

2.1.2. Tertiary Protein Structure3 min

2.1.3. Example: Point Mutation in Secondary Structure3 min

2.2.1. α-helix3 min

2.2.2. Properties of α-helix5 min

2.2.3. Example: Properties of an Alpha Helix3 min

2.2.4. Example: Point Mutation in Alpha Helix4 min

2.2.5. Practice: Alpha-Helix3 min

2.3.1. β-Sheet4 min

2.3.2. β-turns and loops5 min

2.3.3. Example: Beta-Turns2 min

2.3.4. Example: H-bonding in Beta-Sheets2 min

2.3.5. Example: Beta-Barrel Channels4 min

2.3.6. Practice: Stacked Beta-Sheets

2.4.1. Anfinsen's Experiment8 min

2.4.2. Thermodynamics of Protein Folding7 min

2.4.3. Example: Urea2 min

2.4.4. Practice: Protein Folding2 min

2.4.5. Hydropathy7 min

2.5.1. Amino Acids10 min

2.5.2. Example: Similar Amino Acids3 min

2.5.3. Example: Directed Mutagenesis3 min

2.6.1. Peptide Bond6 min

2.6.2. Peptide Bond Angles3 min

2.6.3. Example: Peptide Chain4 min

2.6.4. Example: Peptide Bond Angles2 min

2.6.5. Practice: Peptide Bond Resonance2 min

2.7.1. Acids-Base Definitions, pH, pKa5 min

2.7.2. pKa and Ionization State8 min

2.7.3. pKa of Amino Acids10 min

2.7.4. Amino Acid Isoelectric Point5 min

2.7.5. Practice: pKa of Side Chains4 min

2.Q. Amino Acids: Checkpoint Quiz7 Qns

2.P.1. Practice: Role of Amino Acids in an Active Site

2.P.2. Practice: Amino Acids

3. Enzymes

1.1hr

3.1.1. Enzyme Classes7 min

3.1.2. Active Site3 min

3.1.3. Enzyme Mechanisms7 min

3.1.4. Cofactors/Coenzymes2 min

3.1.5. Enzyme Regulation3 min

3.1.6. Example: Enzyme Classes58 sec

3.1.7. Example: Enzyme Mechanics1 min

3.1.8. Example: Coenzymes and Cofactors33 sec

3.1.9. Practice: Enzyme Catalyzed Reactions1 min

3.2.1. Enzyme Kinetics3 min

3.2.2. Michaelis-Menten Equation5 min

3.2.3. Lineweaver-Burke Plot2 min

3.2.4. Example: Lineweaver Burke Plot1 min

3.2.5. Allosteric Enzymes11 min

3.2.6. Reversible/Irreversible Inhibition3 min

3.2.7. Types of Irreversible Inhibition3 min

3.2.8. Competitive Inhibition2 min

3.2.9. Uncompetitive Inhibitors2 min

3.2.10. Non-Competitive Inhibition3 min

3.2.11. Example: Enzyme Inhibition2 min

3.2.12. Practice: Enzyme Kinetics52 sec

3.2.13. Cheatsheet: Summary of Inhibitors

3.Q. Enzymes4 Qns

3.P.1. Hemeoglobin and anaeobic regulation

4. Energy Transfer

57min

4.1.1. ATP Synthesis10 min

4.1.2. ATP and the Proton Motive Force (PMF)6 min

4.1.3. ATP production: Cheatsheet

4.2.1. Intro to Metabolism7 min

4.2.2. Gibbs Free Energy10 min

4.2.3. High Energy Intermediates9 min

4.2.4. Oxidation-Reduction Reactions6 min

4.2.5. Example: Oxidation-Reduction Reactions3 min

4.2.6. Example: Gibbs Free Energy3 min

4.2.7. Free energy of ATP52 sec

4.2.8. Coupled Reactions1 min

4.Q. Introduction to Metabolism4 Qns

5. Metabolism: Universal Pathways

42min

5.1.1. Glycolysis11 min

5.1.2. ATP production in Glycolysis1 min

5.1.3. Triose Phosphate Isomerase2 min

5.1.4. Glycolysis1 min

5.1.5. Glycolysis: Cheatsheet

5.2.1. Lactate Dehydrogenase2 min

5.2.2. Alcohol Fermentation42 sec

5.2.3. Anaerobic Metabolism1 min

5.2.4. Lactate Formation55 sec

5.2.5. Anaerobic respiration30 sec

5.3.1. Pyruvate Dehydrogenase6 min

5.3.2. Pyruvate Dehydrogenase Complex38 sec

5.3.3. Regulation of PDC1 min

5.4.1. Citric Acid Cycle8 min

5.4.2. The Citric Acid Cycle1 min

5.4.3. The Citric Acid Cycle: Cheatsheet

5.4.4. Structure of Mitochondria3 min

5.P.1. Mitochondria

5.P.2. P/O ratios

6. Metabolism: Plant-specific processes

31min

6.1.1. Light-Dependent Reactions of Photosynthesis [detailed]10 min

6.1.2. Non-Cyclic and Cyclic Versions of Light-Dependent Reactions3 min

6.1.3. Calvin Cycle8 min

6.1.4. New Lesson2 min

6.1.5. New Lesson45 sec

6.1.6. New Lesson3 min

6.1.7. Wize Concept Check1 min

6.P.1. New Practice Question

6.P.2. New Practice Question

6.P.3. New Practice Question

6.P.4. Practice: Photosynthesis2 min

6.P.5. New Practice Question

6.P.6. New Practice Question

Mock Exams

ME.1. Exam 1 (Midterm) - Mock Assessment40 Qns

ME.2. Final Exam - Mock Assessment52 Qns

ME.1 Exam 1 (Midterm) - Mock Assessment

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Exam 1 (Midterm) - Mock Assessment

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