BIOL 202

McGill

Course Overview

Lessons & Practice

I. Welcome

1. Chromosomal Basis of Inheritance

1.3hr

1.1.1. The Gene and the Genome10 min

1.1.2. Practice 11 min

1.2.1. Phases of the Cell Cycle5 min

1.2.2. Practice 12 min

1.3.1. Mitosis and Cytokinesis7 min

1.3.2. Cytokinesis2 min

1.3.3. Practice 13 min

1.3.4. Practice 23 min

1.3.5. Practice 3

1.3.6. Practice 4

1.3.7. Ploidy & C-value coefficients5 min

1.4.1. Meiosis I10 min

1.4.2. Chromosomal Crossover3 min

1.4.3. Meiosis Nomenclature3 min

1.4.4. Practice 1

1.4.5. Practice 2

1.4.6. Practice 3

1.5.1. Meiosis II5 min

1.5.2. Practice 1

1.5.3. Practice 2

1.5.4. Practice 3

1.5.5. Practice 4

1.5.6. Example: Graphing Ploidy & C-value Coefficients4 min

1.6.1. Chromosomal Nondisjunction, Aneuploidy and Polyploidy6 min

1.6.2. Example2 min

1.6.3. Practice 1

1.6.4. Practice 27 min

2. Classical Diploid Genetics

1.4hr

2.1.1. History of Mendelian Genetics4 min

2.1.2. Basics of Probability for Genetics5 min

2.1.3. Example 12 min

2.1.4. Example 22 min

2.1.5. Practice 1

2.2.1. Alleles3 min

2.2.2. Genotype and Phenotype5 min

2.3.1. Mendel's Law of Segregation10 min

2.3.2. Mendel's Law of Independent Assortment6 min

2.3.3. Punnett Square Rules4 min

2.3.4. Example 15 min

2.3.5. Example 29 min

2.3.6. Practice 1

2.3.7. Practice 2

2.3.8. Practice 3

2.3.9. Practice 4

2.3.10. Cheatsheet: Inheritance Terminology

2.4.1. Forked Line Method5 min

2.4.2. Probability Method4 min

2.4.3. Practice 1

2.4.4. Practice 2

2.5.1. Practice 1

2.5.2. Practice 2

2.5.3. Practice 3

2.6.1. Incomplete Dominance and Co-Dominance3 min

2.6.2. Example4 min

2.6.3. Practice 1

2.7.1. Inheritance of Autosomal Traits9 min

2.7.2. Example 1

2.7.3. Example 2

2.8.1. Inheritance of X-linked Traits

2.8.2. Example 13 min

2.8.3. Example 2

2.8.4. Example 3

3. Extrachromosomal Genetics

15min

3.1.1. Lateral Gene Transfer5 min

3.2.1. Mitochondrial DNA Inheritance3 min

3.2.2. Fission and Fusion of Mitochondria6 min

4. Molecular Aspects of Mutagenesis, Mutations, and Repair of Mutations

1.1hr

4.1.1. Types of DNA Mutations9 min

4.1.2. Practice 1

4.1.3. Practice 2

4.1.4. Sources of Mutation: Tautomeric Shifts7 min

4.1.5. Sources of Mutation: DNA Slippage5 min

4.1.6. Example: Tautomeric Shifts4 min

4.1.7. Sources of Mutation: Copy Number Variations3 min

4.1.8. Sources of Mutation: Mobile Elements7 min

4.2.1. Repair of Mutations During Replication [Exonuclease Activity and Mismatch Repair]10 min

4.2.2. Repair of Mutations by Mutagens [Nucleotide Excision Repair]3 min

4.2.3. Practice 12 min

4.3.1. Repair of DNA Double Stranded Breaks [detailed]9 min

4.3.2. Practice 12 min

4.4.1. Duplications, Deletions and Inversions4 min

4.4.2. Practice 1

5. Eukaryotic Chromosome Mapping in Diploids

36min

5.1.1. Genetic Linkage4 min

5.1.2. The Configuration Of Linked Genes 4 min

5.1.3. The Chi-Square Test and Linkage Analysis12 min

5.1.4. Example Problem - Chi-Square Test 7 min

5.1.5. Practice 1

5.1.6. Practice 2

5.1.7. Practice 3

5.1.8. Practice 4

5.1.9. Practice Question - Chi-Square

5.1.10. Recombination Frequencies and Linkage Maps6 min

5.2.1. Gene Mapping4 min

6. Population Genetics and Quantitative Inheritance

29min

6.1.1. Population Genetics & Selection

6.1.2. Hardy-Weinberg Principle5 min

6.1.3. Hardy-Weinberg Equation5 min

6.1.4. Example4 min

6.1.5. Practice 1

6.1.6. Practice 2

6.1.7. Example: Applying HWE during experimentation5 min

6.1.8. Practice: Assortative Mating10 min

7. Molecular Aspects of Genetics and Genetics Analysis

33min

7.1.1. Centrifugation2 min

7.1.2. Chromatography4 min

7.1.3. Practice

7.2.1. Protein Detection Techniques6 min

7.2.2. SDS-PAGE (Electrophoresis)6 min

7.2.3. Mass Spectrometry2 min

7.2.4. Practice 1

7.3.1. (Agarose) Gel Electrophoresis 3 min

7.4.1. Proteomics4 min

7.4.2. Chromatin Immuno-Precipitation (ChIP) 2 min

7.4.3. Practice 1

7.4.4. Practice 2

7.4.5. Practice 3

7.5.1. Southern Blot2 min

7.5.2. Northern Blot2 min

7.5.3. Practice

8. Molecular Markers, Gene Cloning, and other Molecular Tools

53min

8.1.1. Cloning and DNA libraries17 min

8.1.2. Plasmids2 min

8.1.3. Restriction Enzymes or Endonucleases3 min

8.1.4. Restriction Enzymes7 min

8.1.5. Digestion and ligation

8.1.6. Gene Cloning5 min

8.2.1. Genome Editing11 min

8.2.2. CRISPR [detailed]9 min

8.2.3. Practice 1

8.2.4. Practice 2

9. Genomics and Bioinformatics

9min

9.1.1. DNA Sequencing9 min

10. Cancer Genetics

36min

10.1.1. Causes of Cancer14 min

10.1.2. Cancer Treatments9 min

10.1.3. How does cancer grow?7 min

10.1.4. Example: Cancer Causes3 min

10.1.5. Example: Cancer Treatment3 min

Mock Exams

ME.1. Midterm Exam - Mock Assessment22 Qns

ME.2. Final Exam - Mock Assessment39 Qns

ME.2 Final Exam - Mock Assessment

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Final Exam - Mock Assessment

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