SC/BIOL 2040 3.00

York U

Course Overview

Lessons & Practice

I. Welcome

2 min

1. Review

1.8hr

1.1.1. Review of DNA Structure10 min

1.1.2. Practice 12 min

1.1.3. Practice 2

1.2.1. History of Mendelian Genetics4 min

1.2.2. Basics of Probability for Genetics5 min

1.2.3. Example 12 min

1.2.4. Practice 1

1.2.5. Example 22 min

1.3.1. Alleles3 min

1.3.2. Genotype and Phenotype5 min

1.4.1. Incomplete Dominance and Co-Dominance3 min

1.4.2. Example4 min

1.4.3. Practice 1

1.5.1. Mendel's Law of Segregation10 min

1.5.2. Mendel's Law of Independent Assortment6 min

1.5.3. Punnett Square Rules4 min

1.5.4. Example 15 min

1.5.5. Example 29 min

1.5.10. Cheatsheet: Inheritance Terminology

1.6.1. Forked Line Method5 min

1.6.2. Probability Method4 min

1.6.3. Practice 1

1.6.4. Practice 2

1.7.1. Pedigree Analysis9 min

1.8.1. Inheritance of Autosomal Traits9 min

1.8.2. Example 1

1.8.3. Example 2

1.9.1. Inheritance of X-linked Traits

1.9.2. Example 13 min

2. Gene Interactions

43min

2.1.1. Introduction to Genetic Interactions 25 sec

2.2.1. Complementation 7 min

2.2.2. Example Problem2 min

2.2.3. Practice Question 4 min

2.2.4. Epistasis 5 min

2.2.5. Redundancy 2 min

2.2.6. Practice Question 2 min

2.2.7. Genes in a pathway 3 min

2.2.8. Penetrance versus Expressivity 1 min

2.2.9. Example Problem4 min

2.2.10. Cheatsheet - Summary of genetic interactions

2.3.1. Blood Types2 min

2.3.2. Practice 1

2.3.3. Pleiotropy, Epistasis and Polygenic Inheritance5 min

2.3.4. Practice 2

2.3.5. Practice 3

2.3.6. Example: Epistasis5 min

2.Q. Checkpoint Quiz2 Qns

3. Mitosis/Meiosis and Linkage

1.7hr

3.1.1. Cell Theory

3.2.1. Phases of the cell cycle

3.3.1. Mitosis and Cytokinesis

3.4.1. Practice Questions7 Qns

3.5.1. Meiosis I10 min

3.5.2. Chromosomal Crossover3 min

3.5.3. Meiosis Nomenclature3 min

3.5.4. Practice 1

3.5.5. Practice 2

3.5.6. Practice 3

3.6.1. Meiosis II5 min

3.6.2. Example: Graphing Ploidy & C-value Coefficients4 min

3.7.1. Genetic Linkage4 min

3.7.2. Recombination Frequencies and Linkage Maps6 min

3.7.7. Genetic Linkage8 min

3.7.8. Mapping 2 min

3.7.9. Crossovers 4 min

3.7.10. The Configuration Of Linked Genes 4 min

3.7.11. Example: Genes11 min

3.7.12. Interference 5 min

3.7.13. Example: Interference 2 min

3.7.14. Practice: Genotypes1 min

3.7.15. Practice: Genes2 min

3.7.16. Practice: Daughter Cells7 min

3.7.17. The Chi-Square Test and Linkage Analysis12 min

3.7.18. Example Problem - Chi-Square Test 7 min

3.7.19. Practice Question - Chi-Square

4. Gene Expression

1.8hr

4.1.1. The Central Dogma of Biology4 min

4.1.2. Practice 1

4.1.3. Practice 22 min

4.1.4. Practice 32 min

4.2.1. Genes and mRNA8 min

4.2.2. General Structure of mRNA4 min

4.2.3. The Genetic Code8 min

4.2.4. Reading Frame3 min

4.2.5. Practice 13 min

4.2.6. Practice 22 min

4.2.7. Practice 32 min

4.2.8. Practice 43 min

4.2.9. Summary of Genes and mRNA

4.3.1. Initiation8 min

4.3.2. Elongation7 min

4.3.3. Termination4 min

4.3.4. Practice 14 min

4.3.5. Practice 22 min

4.3.6. Practice 3

4.4.1. Transcription In Eukaryotes9 min

4.4.2. Practice 1

4.5.1. RNA Maturation in Eukaryotes8 min

4.5.2. Example 3 min

4.5.3. Practice 11 min

4.5.4. Practice 23 min

4.5.5. mRNA Maturation - Theory3 min

4.6.1. Translation into Proteins9 min

4.6.2. Differences in Eukaryotic and Prokaryotic Translation3 min

4.6.3. Example 15 min

4.6.4. Example 2

4.6.5. Transcription vs. Translation Chart

4.6.6. Practice 2

4.6.7. Practice 1

5. Norms of Reaction

6. Gene Regulation

1.2hr

6.1.1. Introduction to Regulation of Gene Expression4 min

6.1.2. Prokaryotic Levels of Regulation6 min

6.1.3. Prokaryotic Regulatory Proteins5 min

6.1.4. Types of Transcriptional Regulation5 min

6.1.5. Practice 1

6.1.6. Practice 2

6.1.7. Practice 3

6.2.1. The Tryptophan (Trp) Operon5 min

6.2.2. Trp Operon Attenuation8 min

6.2.3. The Trp Operon Summary

6.3.1. The Lac Operon5 min

6.3.2. Practice 1

6.3.3. Practice 2

6.3.4. Practice 3

6.4.1. The Lac Operon [detailed]5 min

6.4.2. The Lac Operon & Glucose Regulation [detailed]5 min

6.4.3. Lac Operon Summary

6.4.4. Example 1

6.4.5. Example 2

6.4.6. Practice 1

6.5.1. The Maltose (mal) Operon 4 min

6.6.1. Epigenetic Gene Regulation5 min

6.6.2. X-Chromosome Inactivation4 min

6.6.3. Practice 1

6.6.4. Practice 2

6.7.1. Transcription Factors, Enhancers and Repressors3 min

6.7.2. Practice 1

6.7.3. Practice 2

6.8.1. Eukaryotic Post-Transcriptional Regulation6 min

6.8.2. Practice 1

6.8.3. Practice 2

6.9.1. Translational and Post-translational Regulation2 min

6.9.2. Practice

7. Variation

55min

7.1.1. Introduction to Genetic Variability1 min

7.2.1. Additive Inheritance 8 min

7.2.2. Environmental Modification 6 min

7.2.3. Example Problem 2 min

7.2.4. Practice Question1 min

7.3.1. Polymerase Chain Reaction (PCR) 5 min

7.3.2. Gel Electrophoresis 4 min

7.3.3. Synthesizing PCR primers 4 min

7.3.4. PCR Practice Problem 5 min

7.3.5. Practice Question 7 min

7.3.6. Practice Question

7.3.7. PCR stages

7.4.1. DNA Sequencing 6 min

7.4.2. Example Problem2 min

7.4.3. Practice Question 2 min

7.4.4. New Cheatsheet3 min

7.Q. Checkpoint Quiz9 Qns

8. Genetic Association

1.4hr

8.1.1. Types of Mutations 15 min

8.1.2. Introduction to DNA Polymorphism 4 min

8.1.3. Single Nucleotide Polymorphism (SNPs) 11 min

8.1.4. Example Problem 4 min

8.1.5. Practice Question 1.6 min

8.1.6. Practice Question. 2 2 min

8.1.7. Simple Sequence Length Polymorphism (SSLPs)5 min

8.1.8. Indel & Large Scale Chromosomal Changes4 min

8.1.9. Example Problem 5 min

8.1.10. Practice Question55 sec

8.1.11. Practice Question3 min

8.1.12. Practice Question4 min

8.1.13. Polymorphism in association with mRNA and proteins. 13 min

8.1.14. Example Problem2 min

8.1.15. Practice Question 2 min

8.1.16. Practice Question3 min

8.1.17. Summary of Genetic Variations 2 min

9. RNAi and GSD

11min

9.1.1. Cytoplasmic mRNA Degredation11 min

10. Development

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Answered

Aseel Y

Hi there, I just want to ask why Homeostasis section is not available!

Danielle S

Instructor

Thank you for bringing this to our attention and your patience in allowing us to solve the issue!

The chapter now has the content ready for you to explore and review.

Answered

Anonymous

Is glycolysis not covered in this course?

Lila H

Instructor

It is currently included in Section 5 "Energy and Metabolism"

Answered

Anonymous

What is the difference between gene flow and genetic drift 

Isaura F

Instructor

Gene flow is the transfer of genetic information from one population to another. Genetic drift is the variation of the relative frequency of a particular allele (version of a gene) within a population. Hope this helps!

Answered

Shannon W

What's neurons?

Marlon B

A nerve cell

Answered

Alexis E

whats a hydrogen bond?

Elizabeth P

Instructor

Hydrogen bonds involve a H atom that is covalently bonded to a highly electronegative atom (F, O, N) causing it to be partially stripped of its electrons by that atom.

This causes a transient attractive interaction to form between the partially positive H with another partially negative (electronegative) atom. Example: water (two Hs bound to one O) loves to interact with other water molecules in that way.

Hydrogen bonds are not covalent bonds, they are much weaker.

Answered

Anonymous

Are there any parts of the human body that get oxygen directly from the air and not from the blood?

Isaura F

Instructor

Seems like the outer layers of skin and outer cornea (of your eyes) are able to get oxygen directly from air. 

Answered

Laura P

How does climate change affect wildlife in ontario? 

Isaura F

Instructor

"In Ontario, [one] can expect average temperatures to rise by as much as 3 to 8 degrees Celsius over the next century. Warmer temperatures will result in milder winters, longer growing seasons and a higher frequency of severe weather events such as record-breaking storms, floods, droughts and heat waves." For more info, check out: http://www.health.gov.on.ca/en/common/ministry/publications/reports/climate_change_toolkit/climate_change_health_modelling_study.pdf

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