Practice Problem 1

Which of the following statements are true, and which are false? Explain.

a. Histones are negatively charged.
b. The histone octamer consists of four H1, each paired with one of H2A, H2B, H3, or H4.
c. Most chromatin takes the form of euchromatin.
d. The 5’ and 3’ designations for the ends of nucleic acids indicates whether a phosphate or hydroxyl group is exposed at the end of the molecule.

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