[Solution] The expression of the Wingless (Wnt) gene…

The expression of the Wingless (Wnt) gene in drosophila results in the normal development of fly wings. However, when the Wnt gene is not expressed, the flies have develop very short wings. You are studying a particular fly in which the expression levels of Wnt is linked to a histone acetylase, which acetylates lysines near the Wnt gene. How might this acetylation affect the fly?

Wnt transcription will decrease.

The chromatin around the Wnt gene would de-condense.

The fly would develop very short wings

The chromatin around the Wnt gene would adopt a heterochromatin state.

The acetylation would have no effect on Wnt transcription.

I don't know

Practice: Eukaryotic Cells

Certain proteins are nearly universal amongst eukaryotic cells. However, when comparing different organisms, the sequences of the genes that encode these proteins can vary quite a bit.
Provide two explanations as to how this may be possible.

Practice Problem 5

A histone-modifying enzyme adds acetyl groups to lysines on the tails of nucleosome core histones. Lysine is normally positively charged, but this modification neutralizes the charge. What might happen if you mutated this enzyme so that it became non-functional?

The expression of the Wingless (Wnt) gene in drosophila results in the normal d…

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