Wize University Organic Chemistry Textbook > Carboxylic Acid Derivatives (Nucleophilic Acyl Substitutions)
Hydrolysis of Acid Derivatives
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Hydrolysis of Acid Halides and Anhydrides
Acid Halides and anhydrides can be hydrolyzed back to carboxylic acids. Since these are reactive species, hydrolysis releases heat.
Wize Concept
Reactions that release heat are called exothermic.
Wize Tip
Hydrolysis reactions are those which involve the addition of water.
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Hydrolysis of Esters and Amides
Esters and amides can be hydrolyzed back to carboxylic acids. Since these are less reactive species, hydrolysis requires heat.
Wize Concept
Reactions that release heat are called endothermic.
Wize Tip
Hydrolysis reactions are those which involve the addition of water.