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A cell has a mutation that results in higher expression of the gene encoding p2…

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Wize University Biology Textbook > DNA Replication & Repair

Types of DNA Mutations

8 Activities

Wize University Biology Textbook > The Cell Cycle

Control of Cell Cycle

5 Activities

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A cell has a mutation that results in higher expression of the gene encoding p21. What would happen to the cell?
More Types of DNA Mutations Questions:
The bong mutant of a yeast species Saccharomyces causes them to be restricted to generating ATP through glycolysis alone. Which of the follow statements could be a possible role of this mutation?
Practice: Protein Structure
A missense mutation arises in the amino acid sequence in which the residue R is substituted for A. Which of the following is most likely true?
Which of the following mutations would not affect translation?
Mutation
You are studying the genetic codes of three phenotypically identical E. coli bacteria: HB99, HB100 and HB101. While studying their DNA sequences, you note that a point mutation has in a the same gene in each of the E. coli strains. The gene encodes for an enzyme required to methylate lysine 27 on Histone 3: H3K27.
HB99 sequence: ATGCGTCACGTCGA
HB100 sequence: ATGCGTTACGTCGA
Mutation
You are studying the genetic codes of three phenotypically identical E. coli bacteria: HB99, HB100 and HB101. While studying their DNA sequences, you note that a point mutation has occurred in the same gene in each of the E. coli strains. The gene encodes for an enzyme required to methylate lysine 27 on Histone 3: H3K27.
HB99 sequence: ATGCGTCACGTCGA
HB100 sequence: ATGCGTTACGTCGA
Which of the following mutations would not affect translation?
MCAT Practice Question
The bong mutant of a yeast species Saccharomyces causes them to be restricted to generating ATP through glycolysis alone. Which of the follow statements could be a possible role of this mutation?
A missense mutation arises in the amino acid sequence in which the residue R is substituted for A. Which of the following is most likely true?
Practice: Protein Structure
A missense mutation arises in the amino acid sequence in which the residue R is substituted for A. Which of the following is most likely true?
MCAT Practice Question
The bong mutant of a yeast species Saccharomyces causes them to be restricted to generating ATP through glycolysis alone. Which of the follow statements could be a possible role of this mutation?
A human cell has received a mutation and is unable to produce actin. What would be the result after mitosis?
Retinoblastoma is a type of eye cancer caused by:
A. a mutation in the Rb transcriptional factor that its inhibited binding to DNA
B. a mutation in p53 that prevents it from recognition damaged DNA
Which of the following is most likely to occur due to a mutation in p21?
Mutation that leads to the substitution of one amino acid for another are called?
Which of the following is consistent with the observation that cancers have an important epigenetic component?
Some tumor supressor proteins are involved in DNA repair
Some carcinogens are not mutagens
A nonsense mutation in the drosophila bicoid gene would result in which of the following?
After two rounds of DNA replication an SNP has been introduced into a genes open reading frame but the protein product is the exact same as the gene product from the sequence without the SNP. What type of mutation is this?
If a single base pair was inserted into DNA coding for the second exon of a eukaryotic mRNA transcript with three exons and two introns, which of the following statements is most likely true about the resulting protein?
Imagine you are studying an E. coli gene that codes for a specific enzyme. You have isolated a mutant for this enzyme, where E. coli produces a shorter than normal form of the polypeptide, and thus the enzyme is not functional. What type of mutation most likely led to this mutant?
Which of the following are directly responsible for ensuring that cells do not replicate in the event of DNA damage?
Which of the following describes a nonsense mutation?
You discover through your genetic counsellor that you have an alteration in an mitochondrial transit sequence. Which of the following characteristics of your nuclear genome would have been altered?
The bong mutant of a yeast species Saccharomyces causes them to be restricted to generating ATP through glycolysis alone. Which of the follow statements could be a possible role of this mutation?
Which of the following could affect all of the primary, secondary, and tertiary structure
of a protein?
Practice: Protein Structure
A missense mutation arises in the amino acid sequence in which the residue R is substituted for A. Which of the following is most likely true?
Which of the following mutations would not affect translation?
Mutation
You are studying the genetic codes of three phenotypically identical E. coli bacteria: HB99, HB100 and HB101. While studying their DNA sequences, you note that a point mutation has in a the same gene in each of the E. coli strains. The gene encodes for an enzyme required to methylate lysine 27 on Histone 3: H3K27.
HB99 sequence: ATGCGTCACGTCGA
HB100 sequence: ATGCGTTACGTCGA
Which DNA mutation(s) involve changes to a single basepair?
More Control of Cell Cycle Questions:
What would happen if Rho production was inhibited?
You take readings of protein concentrations from a cell and record them in a table. What phase of the cell cycle is the cell in?
APC - 10mM
Cdc25 - 50mM
Which stage-shift requires polyubiquination of regulatory cyclin-CDK1 protein?
To move from G+ phase to S phase, Cyclin-CDK2 must....
A mutation in a bacterial cell causes the cell to have nonfunctional CDK1s What would be the result?
Cyclin regulation of the cell cycle is a form of _________ (long term or short term) cell signaling. We know this because ....
(fill in the blank and finish this sentence)
What would happen if S-Cdk (normally at high levels during S phase) was present during mitosis initiation but M-Cdk was not?
How many checkpoints are there in the cell cycle?
Which of the following scenarios would trigger programmed cell death or apoptosis?
Which cyclin corresponds to the graph region labelled (2)?
Which of the following are negative regulators of cell cycle? Select all that apply
Which of the following describes the function of p53 in regulation cell cycle?
1. p53 activates transcription of p21 which inhibits G1-S Cdk activation
2. DNA damage activates p53
Which of the following results in arrest of the cell cycle?
Propose an imaging technique that you could use to monitor the progression of a cell through the cell cycle.
How many of the following correspond to cell cycle positive regulators?
p53
Rb
Which of the following are negative regulators of cell division? Select all that apply.
At the end of the cell cycle, a cell is found to have an extra chromosome 3. Which cell cycle checkpoint did this cell miss?
Cyclins and cyclin-dependent kinases (CDKs) are required to push cells from one phase of the cell cycle to another. How do they do this?
At the end of the cell cycle a cell is found to have an extra chromosome 3. Which cell cycle checkpoint did this cell miss?
A cancer cell divides rapidly and never dies. Which of the following would explain the immortality of the cancer cell?
A cancer cell divides rapidly and never dies. Which of the following would explain the immortality of the cancer cell?
At the end of the cell cycle a cell is found to have an extra chromosome 3. Which cell
cycle checkpoint did this cell miss?
Propose an imaging technique that you could use to monitor the progression of a cell through the cell cycle.