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A human cell has received a mutation and is unable to produce actin. What would…

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Wize University Biology Textbook > The Cell Cycle

Mitotic Phase of Cell Cycle

7 Activities

Wize University Biology Textbook > DNA Replication & Repair

Types of DNA Mutations

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Wize University Biology Textbook > Cell Structure

The Cytoskeleton

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A human cell has received a mutation and is unable to produce actin. What would be the result after mitosis?
More Mitotic Phase of Cell Cycle Questions:
If you were to stain proteins in a dividing cell to determine which stage it is in, which of the following protein would you design a fluorescent tag for to visualize a cell in telophase?
A mouse has 20 pairs of chromosomes. How many individual sister chromatids would a mouse cell have at metaphase?
If you were to stain proteins in a dividing cell to determine which stage it is in, which of the following protein would you design a fluorescent tag for to visualize a cell in telophase?
A mouse has 20 pairs of chromosomes. How many individual sister chromatids would a mouse cell have at metaphase?
Mitosis
Colchicine is a chemotherapeutic drug that is used to inhibit the polymerization of tubulin dimers. Which of the following steps of the cell cycle would be most affected by colchicine treatment?
Which of the following is present in meiosis, but not mitosis?
Complete the following table:
Genome
A diploid cell that is 2n = 4 receives a2, b2, and c2 alleles from one parent, and a1, b2, and c2 alleles from the other parent. Alleles a and b are on the same chromosome, while allele c is on another one.
Draw the resulting cell after DNA replication.
Genome
A cell has a genotype a1/a2, c3/c3. Draw the cell before and after DNA replication.
In animal cells, during which phase do centrioles begin to move apart?
Dogs are 2n=782n=78. A somatic dog cell undergoes mitosis. How many chromosomes are there during metaphase and anaphase, respectively?
In which phase of mitosis do chromosomes dencondense?
In which phase of mitosis does the mitotic spindle get broken down?
In which phase do chromosomes become fully condensed?
Complete the following table:
You observe 16 centromeres in a cell under a microscope during interphase, how many chromosomes does the organism have?
During mitosis, all of the following occur except:
A cell that has 4 pairs of chromatids in prophase will have how many chromatids during telophase?
A cell that contains 8 chromosomes at G1 will have how many chromosomes at anaphase?
A cell that contains 24 sister chromatids in prophase would contain how many chromosomes at interphase of the next cell cycle?
Which of the following statements about homologous chromosomes is true?
Dogs are 2n=782n=78. A somatic dog cell undergoes mitosis. How many chromosomes are there during metaphase and anaphase, respectively?
If a cell contained 4 chromosomes during prophase, how many chromosomes and chromatids would it have during prometaphase?
Cell cycle practice problem 3
Complete the following table for a cell that has the genetic formula 2n = 22
Cell cycle practice problem 2
A cell is 2n=82n=8and has the genotype a2/a2, b1/b2, c1/c2, d2/d2. Draw the cell:
a) in "G1 phase"
b) At "metaphase"
Cell cycle practice problem 1
A scientist grows some cells in a medium containing radioactive nucleotides, so all of the DNA within the cells are radioactive. She then transfers the cells to a medium containing normal nucleotides, and allows them to divide. If a cell undergoes one round of mitosis, what percentage of the daughter cells' DNA will be radioactive?
What is the genetic formula for the diploid cell shown below?
Cats have 19 chromosomes and are diploid. How many strands of DNA are there in a non-dividing cat skin cell?
Genome practice problem 1
A cell has the genetic formula n=8n=8. Draw how the cell would look after DNA replication.
Which of the following is different between mitosis metaphase and meiosis metaphase II
Which of the following definitions is incorrect?
Which of the following is not a method for enhancing genetic diversity?
A human cell received a mutation and is unable to produce actin. What would be the result after mitosis?
If a cell contained 4 chromosomes during prophase, how many chromosomes and chromatids would it have during prometaphase?
Which step of mitosis do sister chromatids get separated?
How can FACs be used to quantify the amount of cells in different phases of the cell cycle?
Which of the following describes the differences between mitosis and meiosis?
1. Mitosis occurs in autosomal cells while meiosis in gamete cells
2. Mitosis involves undergoing cell division twice
Anaphase A and B differ in the following way(s). Select all that apply.
Which of the following statements are CORRECT?
1. Mitotic events can be observed with a light microscope
2. Sister chromatids are generated during prophase
Practice: Mitosis
Use the following image of diving onion root cells to answer the following 4 questions:
Practice: Mitosis
Complete the following table based on a cell that is 2n=12
In which of the following groups would you find meiosis?
1. Humans
2. Photosynthetic cyanobacteria
Which of the following is present in meiosis, but not mitosis?
Practice: Cell Cycle 2
A cell is 2n=82n=8and has the genotype a2/a2, b1/b2, c1/c2, d2/d2. Draw the cell:
a) in "G1 phase"
b) At "metaphase"
Cell cycle
In order, what are the phases of the Mitotic (M) phase of the cell cycle?
Telomeres
A human cell as 23 pairs of chromosomes. What is the total number of telomeres found at prophase of mitosis?
If you overheard someone in your biology class say that “plants are haploid and make gametes by mitosis, while animals are diploid and make gametes by meiosis”, would you agree or disagree with this statement, and why?
Which of the following characteristics are the same in both meiosis II and mitosis?
Which of the following is correct regarding the movement of chromosomes during anaphase?
If you were to look at a dividing somatic cell in prometaphase under a microscope, what structures could you see clearly given that you would be able to see all structures of the cell without an appropriate stain?
i. Condensed chrosmosomes
ii. A single centrosome
A flowering plant has 20 pairs of chromosomes. How many telomeres would a gametophyte somatic cell have at prophase of mitosis?
From Term Test 2 Prep: An animal cell is 3n and 6C at prophase. What are the n and C-values of this cell in G1?
From Term Test 2 Prep: A mouse has 20 pairs of chromosomes. How many individual telomeres would a mouse cell have at metaphase?
From Term Test 1 Prep: If you were to stain proteins in a dividing cell to determine which stage it is in, which of the following protein would you design a fluorescent tag for to visualize a cell in telophase?
From Term Test 1 Prep: A mouse has 20 pairs of chromosomes. How many individual sister chromatids would a mouse cell have at metaphase?
Mitosis
Colchicine is a chemotherapeutic drug that is used to inhibit the polymerization of tubulin dimers. Which of the following steps of the cell cycle would be most affected by colchicine treatment?
Mitosis
Researchers often want to visualize what stage of the cell cycle their cells are in. Which of the following proteins could a researcher stain in order to identify cells in metaphase?
1. Actin
2. Tubulin
Chromosome Multiple Choice Question
Which of the following is not true regarding the centromere in metaphase chromosomes?
A cell that contains 24 sister chromatids in prophase would contain how many chromosomes at G1 of the next cell cycle?
A cell that contains 8 chromosomes at G1 will have how many chromosomes after anaphase?
Which of the following statements are CORRECT?
1. Mitotic events can be observed with a light microscope
2. Sister chromatids are generated during prophase
The stage of the cell cycle where one cell splits into two is called _______
How do the daughter cells at the end of mitosis and cytokinesis compare with their parent cell when it was in the G2 stage of the cell cycle?
You are able to observe 16 centromeres in a cell under a powerful microscope during prometaphase – how many sister chromatids does the organism have?
During the entirety of what cell cycle stage(s) can individual chromosomes be observed under a light microscope?
You are studying the cell cycle and observe a cell in the lab with two nuclei, which of the following is a likely explanation?
If you removed a cells’ centrioles with an incredibly fine needle during mitosis, what stage would be affected?
During mitosis, all of the following occur except:
Which of the following is different between mitosis metaphase and meiosis metaphase II
Which of the following is present in meiosis, but not mitosis?
At what phase of mitosis does the nuclear envelope first fragment?
Which of the following is true of cytokinesis in animals?
If a cell contained 4 chromosomes during prophase, how many chromosomes and chromatids would it have during prometaphase?
What is the difference between mitosis metaphase and meiosis metaphase II?
Practice: Mitosis 1
A cell has 10 chromosomes in G1 phase. After prometaphase, how many duplicated chromosomes are present?
Which of the following statements about homologous chromosomes is true?
Practice: Cell Cycle 2
A cell is 2n=82n=8and has the genotype a2/a2, b1/b2, c1/c2, d2/d2. Draw the cell:
a) in "G1 phase"
b) At "metaphase"
Which of the following is present in meiosis, but not mitosis?
A centromere joins a pair of
Is the process of mitosis the same in plant and animal cells?
Which of the following would you make a fluorescent tag for if you wanted to take a fluorescent image of the contractile ring during cytokinesis?
You tag guanines with fluorescent tags and add them to the cell during S phase of the cell cycle. When you look at these chromosomes at metaphase of mitosis using a fluorescent microscope, where on the sister chromosomes would you find fluorescent signal?
If you overheard someone in your biology class say that “plants are haploid and make
gametes by mitosis, while animals are diploid and make gametes by meiosis”, would you
agree or disagree with this statement, and why?
Which of the following characteristics are the same in both meiosis II and mitosis?
Is the process of mitosis the same in plant and animal cells?
Which of the following would you make a fluorescent tag for if you wanted to take a
fluorescent image of the contractile ring during cytokinesis?
If you were to look at a dividing somatic cell in prometaphase under a microscope, what
structures could you see clearly given that you would be able to see all structures of the
cell without an appropriate stain?
You tag guanines with a fluorescent tag and add it to the cell during S phase of the cell cycle. When you look at these chromosomes at metaphase of mitosis using a fluorescent microscope, where on the sister chromosomes would find fluorescent signal?
More Types of DNA Mutations Questions:
The bong mutant of a yeast species Saccharomyces causes them to be restricted to generating ATP through glycolysis alone. Which of the follow statements could be a possible role of this mutation?
Practice: Protein Structure
A missense mutation arises in the amino acid sequence in which the residue R is substituted for A. Which of the following is most likely true?
Which of the following mutations would not affect translation?
Mutation
You are studying the genetic codes of three phenotypically identical E. coli bacteria: HB99, HB100 and HB101. While studying their DNA sequences, you note that a point mutation has in a the same gene in each of the E. coli strains. The gene encodes for an enzyme required to methylate lysine 27 on Histone 3: H3K27.
HB99 sequence: ATGCGTCACGTCGA
HB100 sequence: ATGCGTTACGTCGA
Mutation
You are studying the genetic codes of three phenotypically identical E. coli bacteria: HB99, HB100 and HB101. While studying their DNA sequences, you note that a point mutation has occurred in the same gene in each of the E. coli strains. The gene encodes for an enzyme required to methylate lysine 27 on Histone 3: H3K27.
HB99 sequence: ATGCGTCACGTCGA
HB100 sequence: ATGCGTTACGTCGA
Which of the following mutations would not affect translation?
MCAT Practice Question
The bong mutant of a yeast species Saccharomyces causes them to be restricted to generating ATP through glycolysis alone. Which of the follow statements could be a possible role of this mutation?
A missense mutation arises in the amino acid sequence in which the residue R is substituted for A. Which of the following is most likely true?
Practice: Protein Structure
A missense mutation arises in the amino acid sequence in which the residue R is substituted for A. Which of the following is most likely true?
MCAT Practice Question
The bong mutant of a yeast species Saccharomyces causes them to be restricted to generating ATP through glycolysis alone. Which of the follow statements could be a possible role of this mutation?
A cell has a mutation that results in higher expression of the gene encoding p21. What would happen to the cell?
Retinoblastoma is a type of eye cancer caused by:
A. a mutation in the Rb transcriptional factor that its inhibited binding to DNA
B. a mutation in p53 that prevents it from recognition damaged DNA
Which of the following is most likely to occur due to a mutation in p21?
Mutation that leads to the substitution of one amino acid for another are called?
Which of the following is consistent with the observation that cancers have an important epigenetic component?
Some tumor supressor proteins are involved in DNA repair
Some carcinogens are not mutagens
A nonsense mutation in the drosophila bicoid gene would result in which of the following?
After two rounds of DNA replication an SNP has been introduced into a genes open reading frame but the protein product is the exact same as the gene product from the sequence without the SNP. What type of mutation is this?
If a single base pair was inserted into DNA coding for the second exon of a eukaryotic mRNA transcript with three exons and two introns, which of the following statements is most likely true about the resulting protein?
Imagine you are studying an E. coli gene that codes for a specific enzyme. You have isolated a mutant for this enzyme, where E. coli produces a shorter than normal form of the polypeptide, and thus the enzyme is not functional. What type of mutation most likely led to this mutant?
Which of the following are directly responsible for ensuring that cells do not replicate in the event of DNA damage?
Which of the following describes a nonsense mutation?
You discover through your genetic counsellor that you have an alteration in an mitochondrial transit sequence. Which of the following characteristics of your nuclear genome would have been altered?
The bong mutant of a yeast species Saccharomyces causes them to be restricted to generating ATP through glycolysis alone. Which of the follow statements could be a possible role of this mutation?
Which of the following could affect all of the primary, secondary, and tertiary structure
of a protein?
Practice: Protein Structure
A missense mutation arises in the amino acid sequence in which the residue R is substituted for A. Which of the following is most likely true?
Which of the following mutations would not affect translation?
Mutation
You are studying the genetic codes of three phenotypically identical E. coli bacteria: HB99, HB100 and HB101. While studying their DNA sequences, you note that a point mutation has in a the same gene in each of the E. coli strains. The gene encodes for an enzyme required to methylate lysine 27 on Histone 3: H3K27.
HB99 sequence: ATGCGTCACGTCGA
HB100 sequence: ATGCGTTACGTCGA
Which DNA mutation(s) involve changes to a single basepair?
More The Cytoskeleton Questions:
Practice: Support Fibers
What part of the cytoskeleton consists of tough, durable fibers involved in support only?
Practice: Muscle Contraction
Which of the following cytoskeletal structures is responsible for muscle contractions?
Practice: Tubulin Dimers
Alpha tubulin and beta tubulin dimers make up which of the following?
If you were to stain proteins in a dividing cell to determine which stage it is in, which of the following protein would you design a fluorescent tag for to visualize a cell in telophase?
If you were to stain proteins in a dividing cell to determine which stage it is in, which of the following protein would you design a fluorescent tag for to visualize a cell in telophase?
Mitosis
Colchicine is a chemotherapeutic drug that is used to inhibit the polymerization of tubulin dimers. Which of the following steps of the cell cycle would be most affected by colchicine treatment?
Practice: Support Fibers
What part of the cytoskeleton consists of tough, durable fibers involved in support only?
Practice: Muscle Contraction
Which of the following cytoskeletal structures is responsible for muscle contractions?
Practice: Tubulin Dimers
Alpha tubulin and beta tubulin dimers make up which of the following?
Malformation of what part of the cytoskeleton will result in deformed structure of the cell?
Explain what is happening in this graph with regards to microtubules and their dynamic instability. The x-axis is time and the y-axis is microtubule length.
Which of the following is NOT true about tubulin heterodimers that form microtubules?
The following is true about actin:
Cytoskeleton
Alpha tubulin and beta tubulin dimers make up which of the following?
Practice: Intermediate Filaments
Explain 2 or 3 characteristics about intermediate filaments
Dynein and kinesin walk along what type of cytoskeleton component?
Where are centrioles located?
Practice: Cytoskeleton Review
Complete the following table:
A cell that overexpresses XMAP215 is expected to:
A. have inhibited microtubule formation
B. have increased microtubule formation
Epithelial cells treated with phalloidin would have the following characteristic(s):
A. Impaired tight junction formation
B. Impaired cellular elasticity
Practice: Mitosis 2
What structure is considered the "microtubule organizing centre"?

Which of the following cytoskeletal structure is responsible for muscle contractions?
Practice: Cytoskeleton
What structure is shown in green in the following images?
A.
B.
Practice: Cytoskeleton
What structures are shown in green and red? How did you deduce this?
If you were to look at a dividing somatic cell in prometaphase under a microscope, what structures could you see clearly given that you would be able to see all structures of the cell without an appropriate stain?
i. Condensed chrosmosomes
ii. A single centrosome
Which of the following would you make a fluorescent tag for if you wanted to take a fluorescent image of the contractile ring during cytokinesis?
Which of the following would you make a fluorescent tag for if you wanted to take a
fluorescent image of the contractile ring during cytokinesis?
From Term Test 1 Prep: If you were to stain proteins in a dividing cell to determine which stage it is in, which of the following protein would you design a fluorescent tag for to visualize a cell in telophase?
Mitosis
Colchicine is a chemotherapeutic drug that is used to inhibit the polymerization of tubulin dimers. Which of the following steps of the cell cycle would be most affected by colchicine treatment?
Mitosis
Researchers often want to visualize what stage of the cell cycle their cells are in. Which of the following proteins could a researcher stain in order to identify cells in metaphase?
1. Actin
2. Tubulin
Which of the following cytoskeletal element is associated with myosins?
Dynein and kinesin walk along what type of cytoskeleton component?
What part of the cytoskeleton consists of tough, durable fibres involved in support only?
Which of the following is not a component of the cytoskeleton?
Which of the following would be closest associated to polymerized actin molecules
(microfilaments)?
Which of the following element of the cytoskeleton is associated with nuclear lamina in
the nucleus?
Which of the following is a non-membranous structure?
What part of the cytoskeleton is involved in cell motility (cilia, flagella etc.)?
What is a hollow component of the cytoskeleton?
Which of the following consists of polymerized actin molecules involved in cell crawling?
What part of the cytoskeleton is involved in the internal structures of cilia/flagella?
Which of the following structures is correctly correlated to its function?
If you removed a cells’ centrioles with an incredibly fine needle during mitosis, what stage would be affected?
Where are centrioles located?
Practice: Mitosis 2
What structure is considered the "microtubule organizing centre"?
Write a point form essay outline for the following prompt:
Discuss the roles of cytoskeletal filaments in progression through the cell cycle.
Thesis statement:
What is dynamic instability, and how does it relate to the function of microtubules? Describe an experimental technique that can be used to demonstrate that microtubules have dynamic instability.
If present in a high enough concentration, purified tubulin (or actin) spontaneously polymerizes to form microtubules (or actin microfilaments), as seen in the graph below.
a.What does the slope of the graph indicate?
b. Explain what is happening at times A, B, and C.
Why do you think intermediate filaments don’t have motor proteins?
“Rigor mortis” is a term that describes stiffening of the body following death. With your knowledge of actin-myosin interactions and muscle contraction, explain the molecular basis of rigor mortis.
Write a point form essay outline for the following prompt:
Discuss the importance of structural polarity in cytoskeletal components.
Thesis statement:
Wize Concept Check
What is treadmilling, and how does it relate to the function of actin microfilaments?