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If present in a high enough concentration, purified tubulin (or actin) spontane…

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Wize University Biology Textbook > Cell Structure

The Cytoskeleton

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If present in a high enough concentration, purified tubulin (or actin) spontaneously polymerizes to form microtubules (or actin microfilaments), as seen in the graph below.
a.What does the slope of the graph indicate?
b. Explain what is happening at times A, B, and C.
c.How would the graph change if a microtubule-organizing centre (e.g. centrosome) were added at the beginning of the experiment? Sketch the graph in the space provided below.
More The Cytoskeleton Questions:
Practice: Support Fibers
What part of the cytoskeleton consists of tough, durable fibers involved in support only?
Practice: Muscle Contraction
Which of the following cytoskeletal structures is responsible for muscle contractions?
Practice: Tubulin Dimers
Alpha tubulin and beta tubulin dimers make up which of the following?
If you were to stain proteins in a dividing cell to determine which stage it is in, which of the following protein would you design a fluorescent tag for to visualize a cell in telophase?
If you were to stain proteins in a dividing cell to determine which stage it is in, which of the following protein would you design a fluorescent tag for to visualize a cell in telophase?
Mitosis
Colchicine is a chemotherapeutic drug that is used to inhibit the polymerization of tubulin dimers. Which of the following steps of the cell cycle would be most affected by colchicine treatment?
Practice: Support Fibers
What part of the cytoskeleton consists of tough, durable fibers involved in support only?
Practice: Muscle Contraction
Which of the following cytoskeletal structures is responsible for muscle contractions?
Practice: Tubulin Dimers
Alpha tubulin and beta tubulin dimers make up which of the following?
Malformation of what part of the cytoskeleton will result in deformed structure of the cell?
Explain what is happening in this graph with regards to microtubules and their dynamic instability. The x-axis is time and the y-axis is microtubule length.
Which of the following is NOT true about tubulin heterodimers that form microtubules?
The following is true about actin:
Cytoskeleton
Alpha tubulin and beta tubulin dimers make up which of the following?
Practice: Intermediate Filaments
Explain 2 or 3 characteristics about intermediate filaments
Dynein and kinesin walk along what type of cytoskeleton component?
Where are centrioles located?
A human cell has received a mutation and is unable to produce actin. What would be the result after mitosis?
Practice: Cytoskeleton Review
Complete the following table:
A cell that overexpresses XMAP215 is expected to:
A. have inhibited microtubule formation
B. have increased microtubule formation
Epithelial cells treated with phalloidin would have the following characteristic(s):
A. Impaired tight junction formation
B. Impaired cellular elasticity
Practice: Mitosis 2
What structure is considered the "microtubule organizing centre"?

Which of the following cytoskeletal structure is responsible for muscle contractions?
Practice: Cytoskeleton
What structure is shown in green in the following images?
A.
B.
Practice: Cytoskeleton
What structures are shown in green and red? How did you deduce this?
If you were to look at a dividing somatic cell in prometaphase under a microscope, what structures could you see clearly given that you would be able to see all structures of the cell without an appropriate stain?
i. Condensed chrosmosomes
ii. A single centrosome
Which of the following would you make a fluorescent tag for if you wanted to take a fluorescent image of the contractile ring during cytokinesis?
Which of the following would you make a fluorescent tag for if you wanted to take a
fluorescent image of the contractile ring during cytokinesis?
From Term Test 1 Prep: If you were to stain proteins in a dividing cell to determine which stage it is in, which of the following protein would you design a fluorescent tag for to visualize a cell in telophase?
Mitosis
Colchicine is a chemotherapeutic drug that is used to inhibit the polymerization of tubulin dimers. Which of the following steps of the cell cycle would be most affected by colchicine treatment?
Mitosis
Researchers often want to visualize what stage of the cell cycle their cells are in. Which of the following proteins could a researcher stain in order to identify cells in metaphase?
1. Actin
2. Tubulin
Which of the following cytoskeletal element is associated with myosins?
Dynein and kinesin walk along what type of cytoskeleton component?
What part of the cytoskeleton consists of tough, durable fibres involved in support only?
Which of the following is not a component of the cytoskeleton?
Which of the following would be closest associated to polymerized actin molecules
(microfilaments)?
Which of the following element of the cytoskeleton is associated with nuclear lamina in
the nucleus?
Which of the following is a non-membranous structure?
What part of the cytoskeleton is involved in cell motility (cilia, flagella etc.)?
What is a hollow component of the cytoskeleton?
Which of the following consists of polymerized actin molecules involved in cell crawling?
What part of the cytoskeleton is involved in the internal structures of cilia/flagella?
Which of the following structures is correctly correlated to its function?
If you removed a cells’ centrioles with an incredibly fine needle during mitosis, what stage would be affected?
Where are centrioles located?
Practice: Mitosis 2
What structure is considered the "microtubule organizing centre"?
Write a point form essay outline for the following prompt:
Discuss the roles of cytoskeletal filaments in progression through the cell cycle.
Thesis statement:
What is dynamic instability, and how does it relate to the function of microtubules? Describe an experimental technique that can be used to demonstrate that microtubules have dynamic instability.
Why do you think intermediate filaments don’t have motor proteins?
“Rigor mortis” is a term that describes stiffening of the body following death. With your knowledge of actin-myosin interactions and muscle contraction, explain the molecular basis of rigor mortis.
Write a point form essay outline for the following prompt:
Discuss the importance of structural polarity in cytoskeletal components.
Thesis statement:
Wize Concept Check
What is treadmilling, and how does it relate to the function of actin microfilaments?