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Respiratory Anatomy

The respiratory system consists of
  • The nasal cavity
  • Thoracic cavity
  • the trachea
  • bronchi (primary, secondary and tertiary)
  • bronchioles (terminal and respiratory)
  • Alveoli
  • Diaphragm

Respiratory Physiology

The main functions of the respiratory system include
  • providing gas exchange for the body (O2 in and CO2 out)
  • Regulation of blood pH
  • Speech
  • immune system - defense against microbes (cilia in conduction zone)
  • chemical messenger concentrations
  • trapping and dissolving blood clots

The respiratory system has two main anatomical components
  • The conducting zone – brings air into lungs, “conducts” the air.
  • from the trachea to the tertiary bronchi
  • The respiratory zone – site of gas exchange
  • from the bronchioles to the alveoli
Lung anatomy


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Upper Respiratory Anatomy

Before getting to the lungs air needs to pass through the nose, mouth and specialized structures in the throat, otherwise known as the upper respiratory system.

The Nose

  • Air taken into the nose is heated and moistened before moving into the pharynx
  • Tiny hairs that line the nose trap and block large particles (like dirt and dust) from entering the body
  • Mucus lines the outside of the cell of the nasal cavity to block microscopic particles (dust, bacteria, viruses) from entering the body

The Pharynx

  • Air moves into the pharynx from either the nose or the mouth before moving into the larynx and trachea
  • Food also passes through the pharynx before moving into the esophagus
  • The epiglottis stops food from entering the trachea
  • Cartilage of the larynx supports the epiglottis
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The Larynx

  • Cartilage and ligaments at the top of the trachea form the larynx
  • Air moves into the larynx before traveling down the trachea to the bronchi
  • The larynx contains the vocal cords
  • Vocal cords vibrate when air is pushed out of the lungs, different rates of vibrations gives different sounds
  • Human males after puberty have a an increase in the size of the cartilage that protects the voice box (the Adam's apple) that causes lower frequency vibrations

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Review: Conduction Zone
The conducting zone is the trachea, left and right bronchi, and start of the
bronchioles
  • Cilia help clear the lungs
  • Mucus helps protect the lungs
  • Columnar epithelial cells are durable and sturdy

Respiratory Zone

The respiratory zone is the ends of the bronchioles, and the alveoli
  • No mucus or cilia!
  • Thin (squamous) epithelial cells for gas exchange


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Alveolar Anatomy and Function

Alveoli are made up of
  1. Macrophage cells
  2. Type ll cells
  3. Type l cells
  4. Capillaries

  • Alveoli are good at exchanging gases because
  • they have a thin membrane
  • they have a super high surface area
  • they have a high pressure gradient for gas exchange

  • Rate of Diffusion = gradient(SA)thicknessRate\ of\ Diffusion\ =\ \frac{gradient\left(SA\right)}{thickness}
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Example: Direction of Air Flow

List the correct order of structures that air flows through from being outside the body, to reaching the site of gas exchange.

Nose - pharynx - larynx - trachea - bronchi - bronchioles - terminal bronchiole - alveolus

Practice: Mucus

Mucus is vital to proper respiratory function. Patients suffering from Cystic Fibrosis have hard mucus layers that do not function properly, leading to many complications of the condition. Which of the following are CF patients unable to do well because of their faulty mucus layer?

Practice: Alveoli

Which of the following describe why alveoli are efficient at gas exchange?

Practice: Speaking

The vocal cords, housed at the top of the trachea known as the
, are made of ligaments that vibrate at different
to give different tones when air is pushed out of the
.

Human males tend to produce lower frequency tones after
because the cartilage of the
thickens.