Wize University Biology Textbook > Cellular Respiration
The TCA [Citric Acid / Krebs] Cycle [short]
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The Citric Acid Cycle
Acetyl-CoA enters the citric acid cycle where it is oxidized to CO2. Remember that the Citric Acid cycle is a loop that requires entry of acetyl-CoA to keep going.
- Oxaloacetate combines with acetyl to produce citrate, releasing CoA.
- Each round of the citric acid cycle produces: 3 NADH, 1 FADH2, and 1 GTP.
- All reactions are catalyzed in the mitochondrial matrix, each by a different enzyme.
- The products of the cycle are high energy molecules that can now participate in the electron transport chain to produce lots of ATP.
Balance After Glycolysis + Pyruvate Processing + Citric Acid Cycle
- Glycolysis: 2 pyruvate, 2 ATP, 2 NADH
- Pyruvate processing: 2 acetyl-CoA, 2 NADH
- Citric acid cycle: 6 NADH, 2 FADH2, 2 GTP
NET REACTION: 4 ATP, 10 NADH, 2 FADH2
Where does the Krebs Cycle occur?
Practice: Products of TCA/Citric Acid/Krebs Cycle
What is generated through one turn of the citric acid cycle?
Practice: CO2 Released by Krebs Cycle
How many molecules are released per acetyl group that passes through the Krebs cycle?