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Blood Cells

The process of making blood cells is called hematopoiesis. Blood is made inside the bones (bone marrow)!


Locations of Blood Production
  • Fetuses produce blood in the yolk sac, liver and spleen
  • Kids make blood in axial skeleton bones and long bones
  • Adults make blood in axial skeleton bones
  • Erythro-, thrombo-, or leukopoiesis

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Red Blood Cells
  • Disc-shaped cells that survive around 120 days
  • RBCs have lost their nuclei and most organelles, including mitochondria
  • Can only perform glycolysis for energy
  • Responsible for carrying oxygen and carbon dioxide to tissues
  • Specifically, hemoglobin binds to O2
  • Each can carry up to 4 molecules of O2
  • Responsible for the color of your blood!


Exam Tip
Lifetime of RBCs CAN NEVER be increased!!!

Platelets

  • Role is to initiate the stopping of bleeding
  • First and second parts of hemostasis
  • Have a lifespan of 7-10 days
  • Thrombopoietin from liver can stimulate its production
  • Come from megakaryocytes
  • Very small bits
  • Have many granules and no nucleus

Leukocytes (White Blood Cells)

  • Includes everything other than RBCs or platelets!
  • Involved in the immune response
  • Lifespan can vary a lot depending on leukocyte type (range: hours to years)

Wize Concept

Number of RBCs > Number of Platelets > Number of Leukocytes



Which of the following statements is false?
Regarding hematopoiesis:
Regarding red blood cells, which of the following is false: