High School
SAT
ACT
University
MCAT
LSAT
DAT

Which of the following accurately describes why a single SNP could affect the e…

Related Topics

Wize University Biology Textbook > Gene Expression & Regulation

Introduction to Regulation of Gene Expression

7 Activities

Wize University Biology Textbook > Gene Expression & Regulation

Eukaryotic Post-Transcriptional Regulation

3 Activities

Which of the following accurately describes why a single SNP could affect the expression of more than one protein in eukaryotes?
More Introduction to Regulation of Gene Expression Questions:
For any gene, high rates of transcription don’t necessarily lead to high rates of translation. Why not?
For any gene, high rates of transcription don’t necessarily lead to high rates of translation. Why not?
Which of the following is true regarding prokaryotic operons?
A heat shock protein increases in abundance after exposure to 40°C compared to 24°C. You can visually see the increase in band intensity on a Western blot. You treat your cells with MG132 to block the activity of the proteasome as well as treating the cells with antinomycin to block transcription. Looking at your Western blot, the protein abundance of the heat shock protein decreases over time at the same temperature. What is the most likely reason for this observed decrease?
You have isolated a novel miRNA (miR-007) that affects the development of ears in rabbits.
Loss if MiR-007 leads to a mutant phenotype in which the positioning of the ears is dorsal (wild-type have frontal positioning), and the ears were significantly smaller than the regular size. With further investigations you find that transcription factor (P007) is increased in the mutant type, while the levels of mRNA are the same compared to the wild-type. The levels of proteins have changed.
What type of regulatory protein is P007?
Use the following diagram to answer the true or false questions below.
The two genes are in an operon.
A single operon containing 5 genes has how many promoter regions?
Practice: Gene Mechanisms
You are doing an experiment to determine the mechanism of gene
expression of a bacterial operon responsible for the utilization of glycerol. You know Abc1 is the regulator. You have two strains of the bacteria: one has the normal Abc1 regulator (+abc1), and the other does not (-abc1). You obtain the following results when growing the two strains with and without glycerol:
Describe the mechanism of regulation.
More Eukaryotic Post-Transcriptional Regulation Questions:
You are studying two distinct protein isoforms which seem to arise from the same gene. The two isoforms seem to arise due to a single base pair change found on the mRNA transcript that changes the C at position 854 on the mRNA to a U. As a result of this change, isoform 1 contains the codon CAG (Glutamine) and is translated into a full length protein. However, isoform 2 contains the codon UAG (Stop) and is translated into a truncated protein. This change is most likely the result of which of the following?
The CRISPR/Cas9 system and RNA interference by siRNA are both methods used to knockdown proteins. Which of the following is NOT a key difference between the two techniques?
There is a gene that codes for a protein that is differentially expressed in lung and heart tissue. What are some possible ways that this gene is post-transcriptionally regulated?
Which of the following are neither transcribed nor translated?
TATA box
Enhancer
What is the mechanism by which microRNA affects the production of gene products?
The human body often expresses different proteins or amounts of proteins originating from the same gene in different tissues. Which of the following are possible explanations for this phenomena?
There is a gene that codes for a protein that is differentially expressed in lung and heart tissue. What are some possible ways that this gene is post-transcriptionally regulated?
The CRISPR/Cas9 system and RNA interference by siRNA are both methods used to knockdown proteins. Which of the following is NOT a key difference between the two techniques?
You are studying two distinct protein isoforms which seem to arise from the same gene. The two isoforms seem to arise due to a single base pair change found on the mRNA transcript that changes the C at position 854 on the mRNA to a U. As a result of this change, isoform 1 contains the codon CAG (Glutamine) and is translated into a full length protein. However, isoform 2 contains the codon UAG (Stop) and is translated into a truncated protein. This change is most likely the result of which of the following?
You are studying the mRNA concentration levels of a certain cytokine gene in a cell under different stressful conditions. You notice that when the cell is placed under a chemical stressor, the cytokine protein is present at very high amounts in the cells. Once the stressor is removed, cytokine proteins are almost completely gone. You also observe that in both the stressed and non-stressed conditions, the concentration of the cytokine transcript remains the same. What is the most likely explanation for this observation?
Practice: Eukaryotic Cells
Certain proteins are nearly universal amongst eukaryotic cells. However, when comparing different organisms, the sequences of the genes that encode these proteins can vary quite a bit.
Provide two explanations as to how this may be possible.